Indian J Med Microbiol Close
 

Figure 1: (a and b) Blisters, erosions, and peeling with erythema on the thighs; (c and d) intraepidermal vesicle and vacuolar degeneration of keratinocytes in superficial layer of epidermis (hematoxylin–eosin staining, original magnification c×100, d×400); (e) the arrow indicates the heterozygous mutation (the reverse strand A→G is shown in the upper panel) in the patient; this mutation predicts the amino acid substitution 1436T→C, in the KRT 1 gene, compared with her old brother's (lower panel)

Figure 1: (a and b) Blisters, erosions, and peeling with erythema on the thighs; (c and d) intraepidermal vesicle and vacuolar degeneration of keratinocytes in superficial layer of epidermis (hematoxylin–eosin staining, original magnification c×100, d×400); (e) the arrow indicates the heterozygous mutation (the reverse strand A→G is shown in the upper panel) in the patient; this mutation predicts the amino acid substitution 1436T→C, in the KRT 1 gene, compared with her old brother's (lower panel)