Indian J Med Microbiol Close
 

Figure 1: Clinical photographs of patient 1. (a) Erythematous papules around the mouth and nose at first visit. (b) Patient appearance after 12 months, following 12 consecutive weeks of treatment with oral minocycline and topical tacrolimus. (c) Histological examination of perioral skin papule demonstrates granulomatous infiltration around hair follicles (H and E, ×100). (d) Non-caseating granulomas consisting of lymphocytes, histiocytes, and multinucleated giant cells are observed in the perifollicular area (H and E, ×200)

Figure 1: Clinical photographs of patient 1. (a) Erythematous papules around the mouth and nose at  first visit. (b) Patient appearance after 12 months, following 12 consecutive weeks of treatment with oral minocycline and topical tacrolimus. (c) Histological examination of perioral skin papule demonstrates granulomatous infiltration around hair follicles (H and E,  ×100). (d) Non-caseating granulomas consisting of lymphocytes, histiocytes, and multinucleated giant cells are observed in the perifollicular area (H and E, ×200)