Indian Journal of Dermatology
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   2000| October-December  | Volume 45 | Issue 4  
    Online since July 21, 2009

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ACNE Agminata - Report Of 3 Cases
Raj Pal Singh Punia, Sanjay Kumar, Gurvinder P Thami, Harsh Mohan, Ritambhra Nada, Uma Handa
October-December 2000, 45(4):213-215
Acne agminata or lupus miliaris disseminatus faciei is a chronic granulomatous inflammatory disorder-affecting adults of both sexes which terminates spontaneously with scarring. Histopathologically, the papules show granulomas consisting of epithelioif cells, Gaint cells, with or without caseation necrosis along with periappendigeal lymphomononuclear cell infiltrate in the dermis. The exact aetiopathogenesis of this condition is still unknown. We report 3 cases of this uncommon dermatoses recently seen by us.
[ABSTRACT]   Full text not available  [PDF]
  1,076 121 -
Protease Production In Dermatophytes During Sporulation And Vegetative Phase - Its Role In Pathogenesis And Mating Type Associated Virulence
S Ranganathan, M S Rajith, S Gokul Shankar, S Arun Mozhi Balajee, B N Selvakumar, Mohammad Aejaz
October-December 2000, 45(4):174-181
Different strains of common dermatophytes including different mating strain, collected from clinical, animal and soil sources as also some tester strains, were studied for their proteolytic enzyme activity during vegetative and sporulation phases. Sabouraus’s dextrose broth and Takashio broth were used to induce vegetative and sporulation phases respectively in these dermatophytes. All the strains of T. rubrum showed very low enzyme activity during sporulation when compared vegetative growth phase. In other species of dermatophytes. The enzyme activity was found to be almost similar during both the growth phases. High protease production in association with one mating type of A. vanbreuseghemii was observed. The enzme activity of clinical isolates of the non-anthropophilic species such T. simii, M. nanum and M. gypseum were relatively low when compared to T.mentagrophytes var. interdigitale and T. tonsurans. The severity of the lesion produced by these established the fact that protease in dermatophytes has a define role in pathogenesis. Protease production during sporulation in T. rubrum may be one of the selective advantages of this species. General protease production was found to be independent of mating type in most of the dermatophyte species.
[ABSTRACT]   Full text not available  [PDF]
  756 129 -
Subrata Malakar, Koushik Lahiri, Rita Shah Malakar
October-December 2000, 45(4):223-224
Full text not available  [PDF]
  835 49 -
An Outbreak Of Human Anthrax : A Report Of 15 Cases Of Cutaneous Anthrax
Devinder Mohan Thappa, Shriya Dave, Kaliaperumal Karthikeyan, Shally Gupta
October-December 2000, 45(4):186-191
Anthrax, a zoonotic illness of herbivorous animals has caused epidemics in livestock and in man since antiquity. In India, the disease continues to be endemic, resulting in a few sporadic cases and outbreaks in human population. Such an outbreak was noted at our institute. Clinical and laboratory data of 15 cases of cutaneous anthrax recorded between July 1998 to June 2000 at the Department of Dermatology and STD. JIPMER hospital, Pondicherry was reviewed. There were 8 males and 7 females in our series of 15, with a mean age of 20.3 years (range 11 months to 56 years). The children (10) outnumbered the adults (5). In most of the cases (9) there was history of death of cattle, sheep or goat in the house or in the neighbourhood. The commonest site of cutaneous anthrax was face (7 cases). Regional lymphadenitis occurred in one case and systemic features like fever in four cases. Majority of our cases responded favourably to crystalline penicillin. Smear taken from the vesicle fluid and eschar demonstrated typical large and thick Gram positive bacilli singly or in short chains. The organism could be cultured from cutaneous lesion in six cases only and blood culture was positive for Bacillus anthracis in one case. Cutaneous anthrax is the commonest form of human anthrax. There is increasing evidence to suggest that files and mosquitoes play a role in the transmission of Bacillus anthracis to human beings. Since 20% of untreated cases of cutaneous anthrax develop bacteraemia which leads to rapid death, it is important that the disease is recognized and treated earnestly.
[ABSTRACT]   Full text not available  [PDF]
  782 98 -
Mycetoma Caused By Streptomyces Somaliensis Involving Female Breast
PK Maiti, A Ray
October-December 2000, 45(4):211-212
A 25 year old female presented with discharging sinuses over breasts for 6 years duration. On the basis of FNAC report suggesting non-caseating tuberculosis, she was treated with ATD for 18 months without success. Subsequently, black grains were detected from the discharge of the sinuses and Str. Somaliensis was grown in culture. The site being a covered area was considered as an extremely rare site for occurrence of the disease.
[ABSTRACT]   Full text not available  [PDF]
  772 67 -
G Srikumar, A Hameedultah, R Arunadevi, V Somasundaram, B O Parijatham, G Ilangovan
October-December 2000, 45(4):208-210
Ochronosis is a rare disorder, which presents with distinct clinical and biochemical features. A fifty seven year old male presented with fracture femur, osteoarthritis, Osler’s sign, alkaptonuria and cutaneous ochronosis. Though the clinical progression of his alkaptonuria was typical, he presented interesting features including non-uniting fracture and arthritis of big and small joints.
[ABSTRACT]   Full text not available  [PDF]
  726 95 -
Conversion Disorder Presenting As Neuritic Leprosy
SK Sayal, C S Shrama, A K Malik, Harpeet Singh
October-December 2000, 45(4):198-200
Conversion disorder is not normally listed amongst the conditions in differential diagnosis of leprosy neuropathy. A case conversion reaction who was initially diagnosed as neuritic leprosy is reported. Patient responded to narcosuggestion and psychotherapy.
[ABSTRACT]   Full text not available  [PDF]
  735 83 -
Chronic Dermatophytosis
G Sentamilselvi, C Janki, K Ajitha Dos, A Kamalam, AS Tambiah
October-December 2000, 45(4):168-173
Full text not available  [PDF]
  628 184 -
Homozygous Hypercholesterolaemia With Cutaneous And Tendinous Xanthoma In A Child
Bhabesh Chandra Lahiri, Koushil Lahiri
October-December 2000, 45(4):205-207
A seven year old male child, born of a consanguineous marriage is reported for the rare occurrence of severe hypercholesterolaemia with cutaneous and tendinous xanthoma, mental retardation and eosinophilia in his childhood.
[ABSTRACT]   Full text not available  [PDF]
  713 81 -
Multiple Dermatofibroma
M Manimegalai, Parimalam Kumar, M Jayaraman
October-December 2000, 45(4):196-197
Sixty year old female patient presented with asymptomatic persistent cutaneous nodules and plaques since childhood. Dermatological examination revealed firm, non-tender nodules and plaques (more than fifty) seen over the extremities, thighs, abdomen and back. Histology was consistent with dermatofibroma.
[ABSTRACT]   Full text not available  [PDF]
  717 59 -
Iconography In Dermatology
Karl Holubar, Stella Fatvoic-Ferencic
October-December 2000, 45(4):162-167
Full text not available  [PDF]
  645 100 -
Sero-Prevalence Of Concomitant HIV And Syphilitic Infections Among The STD Clinic Attenders In Calcutta
Kalyani Mitra, Aloke Kr Roy, P K Datta, D K Neogi
October-December 2000, 45(4):182-185
A study was undertaken from October 1997 to March 1998 with 900 subjects, 806 male and 94 female, attending the STD clinics in Calcutta. The study revealed 2.3% HIV seroposivity and 3.88% VDRL positivity among them. Evidence of combined infection (HIV and syphilis) has been observed in10 out of 900 subjects (1.1%). Highest prevalence of HIV seropositivity (13.3%), VDRL reactivity (16.6%) or both (6.6%) was noted among young males up to 30 years of age.
[ABSTRACT]   Full text not available  [PDF]
  635 76 -
Sporadic Multiple Zosteriform Cutaneous Leiomyomas
G P Thami, A J Kanwar, H Mohan
October-December 2000, 45(4):203-204
A case of cutaneous leiomyoma in a zosteriform distribution over right upper limb is described. Differential diagnoses and treatment options are discussed.
[ABSTRACT]   Full text not available  [PDF]
  665 43 -
Psoriasiform Lupus Vulgaris : An Unusual Presentation
Sanjay K Rathi
October-December 2000, 45(4):201-202
A 55 year old woman presented with gradually progressive erythematous scaly plaques, simulating psoriasis, on extremities and face last 20 years. Histology confirmed the diagnosis of lupus vulgaris which is known for its notorious presentations. The case is being reported for its unusual presentation which can cause diagnostic and therapeutic problems.
[ABSTRACT]   Full text not available  [PDF]
  640 59 -
Hanseniasis With Gilbert's Syndrome : A Therapeutic Dilemma?
Sanjay Ghosh
October-December 2000, 45(4):192-195
Therapeutic dilemma often arises in leprosy patients developing jaundice as most of the anti-hanseniasis medicines are hepatotoxic. One 26 year old lady and another 21 year old male having paucibacillary leprosy developed signs of jaundice after onset of treatment with multidrug (MDT) and then they discontinued it. MDT was reintroduced and successfully continued for 6 months with pre-and post- therapy monitoring of liver function test, haemoglobin and other relevant parameters. Total bilirubin (TB) reached maximum upto 3.6 comprising predominantly of unconjugated (3.1); other parameters were normal . The third patient 64 year old male with multibacillary leprosy having past history of recurrent jaundice has also been treated for last 8 months till date with MDT by monitoring. Highest peak of TB was 4.2, unconjugated being 3.4. These represented cases of Gilbert’s syndrome which is a common, benign, familial unconjugated hyperbilirubinaemia without overt haemolysis are often precipitated by drugs. Partial deficiency of bilirubin glucuronosyltransferase is the main causative factor. Hence all patients of leprosy with jaundice does not need discontinuation of therapy. Some patients may have underlying Gilbert’s syndrome when MDT can safely be continued with monitoring.
[ABSTRACT]   Full text not available  [PDF]
  587 69 -
Pansclerotic Morphoea
Nanda Kishore B, Lairai Lawande, J N Shetty
October-December 2000, 45(4):216-217
An eight year old girl presented with progressive stiffness of the right lower limb resulting in joint immobility and apparent shortening causing limitation of movement.
[ABSTRACT]   Full text not available  [PDF]
  577 47 -
A Child With Woolly Hair
T. Y Raghu
October-December 2000, 45(4):225-226
Full text not available  [PDF]
  418 53 -
Review Of Current Literature
Sanjay Ghosh
October-December 2000, 45(4):220-222
Full text not available  [PDF]
  388 43 -
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