The leaf and seed extracts of Azadirachta indicia were tested for antifungl activity against dermatophytes by in vitro and vivo tests. The minimum inhibitory concentration (MIC) of neem seed extract was found to be lower than that neem leaf when tested against different species of Trichophyton and Epidermophyton floccosum. Experimental lesion in guinea pigs healed better after treatment with neem seed extract when compared to untreated control animals.

Forty patients of chronic, stable, plaque psoriasis were treated with different concentrations of crude coal tar (CCT) with varied times of application but constant sun exposure. All concentrations with 8-10 hours of application were found to be equally effective. However, shorter period of application (2 hour) resulted in decreased efficacy. An application of white petrolatum was as effective as crude coal tar when combined with sun exposure.

Fifty vitilgo patients were studied clinically and subjected to thyroid function tests and estimation of glucose and choteserol. Clinical analysis revealed the incidence among new patients to be1.1%. The male/female ratio was 1:1.28. Patient up to 30 years contributed 76%. Vitilgo was obtained in12% and family history of atopy was found in 24% of patients: History of atopy was present in 16% cases. Halo nevus (1 Case), alopecia areata (2 cases) were associated with vitiligo in the study. Abnormality of thyroid function test was detected in 4 cases: it denoted hyperthyroidism in 3 cases and hypothyroidism in1 case. High level of glucose was seen in 3 cases. Cholesterol estimation showed high level in 2 cases.

Eight patients of eumycetoma caused by a variety of fungi were treated with ketoconazole 400 mg/day for a varying length of time. Two patients were cured, 3 improved and 3 did not respond to therapy. The response was considered encouraging and the importance of giving further trials with newer antifungals are stressed.

A case of basidiobolmycosis in a young housewife whose condition responded to a course of fluconazole is reported.

Pretibial myxedema is very rarely associated with Thyrotoxicosis. Here is a case report.

A case of mycetoma, caused by Nocardia species in a 18 year old urban boy, involving nape of neck and adjoining are and upper back, is reported.

Delusional parasitosis is a psychocutaneous disorder rarely seen among the family members. Two case reports are described in which close relatives shared this delusion