ABSTRACT: Adrenalectomy alone in adult male Swiss albino A mice failed to exert any effect on the size (area) of the isolated sebaceous gland from the skin of the back region. Cell renewal and cell growth pattern of this organ as well as the daily sebum production rate also remained unchanged, In the intact, adrenalectomized and castrated-adrenalectomized mice, administration of corticosterone for 15 days at the dose of 100 miug each on alternate day produced a mild effect on the overall activity of sebacuons glands. But in the castrated specimens corticosterone treatment promoted glandular hypertrophy and caused acceleration in the tempo of cell division and cell growth associated with the lipogenic differentiation. This steroid also induced enhancement in the sebum production rate. Identical treatment of Desoxycorticosterone acetate was found to be ineffective in causing any change in the overall activity of sebaceous glands in any group of mice. Gross composition of sebum (assessed by TLC and quantitative densitometry) remained unaltered following removal of testes and/or adrenals as well as after corticosteroid treatments.

ABSTRACT: A case of Monilethrix in a boy is presented. The father had similar affliction of the scalp hair. Scanning electron microscopy established the diagnosis. The medulla was present at the internodal area and no abnormality in the cuticular scales covering the hair shaft was encountered.

ABSTRACT: A 19 year old male presented with multiple atrophic patches with 'Cliff-drop' borders on the trunk of 3 years duration. Clinically and histopathologically, the lesions were consistent with a diagnosis of idiopathic atrophoderma of Pasini and Pierini. It is a distinct entity and is not related to morphoea .

ABSTRACT: A 20-year-old male had five slowly increasing asymptomatic, skin coloured to yellowish white, nontender mobile, hard nodules scattered in the scrotal skin, for the last two years. There was no preceding history of trauma, inflammation or any scrotal disease. He was clinically diagnosed to be sebaceous cysts of the scrotum (SCS) but histopathologically turned out to be idiopathic calcinosis cutis of the scortum (ICCS) Serum calcium and phosphorus levels were normal.