Indian Journal of Dermatology
ORIGINAL ARTICLE
Year
: 2018  |  Volume : 63  |  Issue : 6  |  Page : 475--478

Herpes simplex virus 1 and 2 in herpes genitalis: A polymerase chain reaction-based study from Kerala


Rani Mathew1, Bangalath Najeem2, Kunjumani Sobhanakumary1, Beena Sunny1, Carol Pinheiro3, Balakrishnan Anukumar4 
1 Department of Dermatology and Venereology, Government T D Medical College, Alappuzha, Kerala, India
2 Taluk Head Quarters Hospital, Palakkad, Kerala, India
3 Department of Community Medicine, Government T D Medical College, Alappuzha, Kerala, India
4 National Institute of Virology, Kerala Unit, Palakkad, Kerala, India

Correspondence Address:
Dr. Rani Mathew
Department of Dermatology and Venereology, Government T D Medical College, Alappuzha, Kerala
India

Background: Herpes genitalis is an ulcerating sexually transmitted infection, the clinical importance of which lies in its ability to produce painful and recurrent disease in addition to its potential role as a cofactor in acquisition and transmission of human immunodeficiency virus. In recent years, there are increasing reports of genital herpes due to herpes simplex virus (HSV)-1 from various parts of the world. Molecular diagnostic methods such as polymerase chain reaction (PCR) have got both diagnostic and prognostic significance in genital herpes. Aims: The present study was designed to identify the viral serotype in herpes genitalis patients in our locality, using PCR. Materials and Methods: The specimens from forty herpes genitalis patients were subjected to nested PCR and results were evaluated. Results: PCR was positive for HSV in 83% of cases, of which 58% were due to HSV-1. HSV-2 accounted for maximum number of recurrent herpes. Limitation: Higher sample size would have been more representative. Conclusion: A rising trend of type 1 HSV was observed in herpes genitalis in south India probably due to increasing practice of orogenital sex.


How to cite this article:
Mathew R, Najeem B, Sobhanakumary K, Sunny B, Pinheiro C, Anukumar B. Herpes simplex virus 1 and 2 in herpes genitalis: A polymerase chain reaction-based study from Kerala.Indian J Dermatol 2018;63:475-478


How to cite this URL:
Mathew R, Najeem B, Sobhanakumary K, Sunny B, Pinheiro C, Anukumar B. Herpes simplex virus 1 and 2 in herpes genitalis: A polymerase chain reaction-based study from Kerala. Indian J Dermatol [serial online] 2018 [cited 2020 Oct 29 ];63:475-478
Available from: https://www.e-ijd.org/article.asp?issn=0019-5154;year=2018;volume=63;issue=6;spage=475;epage=478;aulast=Mathew;type=0