Indian Journal of Dermatology
SHORT COMMUNICATION
Year
: 2018  |  Volume : 63  |  Issue : 1  |  Page : 62--65

Adverse reactions due to the bacillus Calmette-Guerin vaccine: Twenty Tunisian cases


Khadija Sellami1, Meriem Amouri1, Sana Kmiha2, Emna Bahloul1, Hajer Aloulou2, Lamia Sfaihi2, R Guirat2, Madiha Mseddi1, T Kamoun2, Mongia Hachicha2, Hamida Turki1 
1 Department of Dermatology, Hedi Chaker Hospital, Sfax, Tunisia
2 Department of Paediatrics, Hedi Chaker Hospital, Sfax, Tunisia

Correspondence Address:
Dr. Khadija Sellami
Department of Dermatology, Hedi Chaker Hospital, Sfax
Tunisia

Background: Bacillus Calmette-Guérin (BCG) vaccine is a widely used vaccine. Management of local BCG complications differs between clinicians, and the optimal approach remains unclear. Aims: We aim to describe the epidemiological, clinical and therapeutic aspects of the BCG vaccine side effects in Sfax. Patients and Methods: This was a retrospective study of all the cases of BCG vaccine adverse reactions recorded in the Dermatology and Paediatrics Departments of Hedi Chaker University Hospital of Sfax over a period of 10 years (2005–2015). Results: Twenty cases of BCG adverse reactions were notified during the study period. Actually, 80% of the patients presented local adverse reactions. The outcome was good in all the followed patients. The rate of disseminated BCG disease was 20%. Biological tests of immunity showed a primary immunodeficiency in three cases, whereas the outcome was fatal in two cases. Conclusion: BCG vaccine adverse reactions range from mild to severe. However, the management of benign local reactions remains unclear. Disseminated BCG disease must alert clinicians to the possibility of a primary immunodeficiency.


How to cite this article:
Sellami K, Amouri M, Kmiha S, Bahloul E, Aloulou H, Sfaihi L, Guirat R, Mseddi M, Kamoun T, Hachicha M, Turki H. Adverse reactions due to the bacillus Calmette-Guerin vaccine: Twenty Tunisian cases.Indian J Dermatol 2018;63:62-65


How to cite this URL:
Sellami K, Amouri M, Kmiha S, Bahloul E, Aloulou H, Sfaihi L, Guirat R, Mseddi M, Kamoun T, Hachicha M, Turki H. Adverse reactions due to the bacillus Calmette-Guerin vaccine: Twenty Tunisian cases. Indian J Dermatol [serial online] 2018 [cited 2021 Jan 23 ];63:62-65
Available from: https://www.e-ijd.org/article.asp?issn=0019-5154;year=2018;volume=63;issue=1;spage=62;epage=65;aulast=Sellami;type=0