Indian Journal of Dermatology
ORIGINAL ARTICLE
Year
: 2017  |  Volume : 62  |  Issue : 2  |  Page : 184--190

Association of dermatoses with duration and quantum of alcohol intake: A comparative cross-sectional study


Yugal Kishor Sharma1, Pankaj Shukla2, Roopa Nayak1, Preeti Kothari1, Aayush Gupta1 
1 Department of Dermatology, Dr. D.Y. Patil Medical College and Hospital, Pune, Maharashtra, India
2 Department of Dermatology, Government Medical College, Bambolim, Goa, India

Correspondence Address:
Aayush Gupta
B-402, The Metropolitan, Near Darshan Hall, Chichwad, Pune - 411. 033, Maharashtra
India

Background: Chronic alcohol intake impacts skin directly, through organ dysfunction or by modifying preexisting dermatoses. However, dermatoses afflicting chronic alcoholics figure in a few studies only. Aim: This study aims to correlate the spectrum of dermatoses in chronic alcoholics with the quantum/duration of alcohol intake and raised liver transaminases. Materials and Methods: Adult males, totaling 196, ascertained to fulfill the Royal College of Psychiatry criteria for chronic alcoholism by the de-addiction center and referred for dermatological consult were enrolled as cases, and similar number of age-/sex-matched teetotallers, as controls. Data emanating from detailed history, clinical examination, and routine liver functions tests were summarized and subsequently analyzed, including statistically using the Chi-square, independent “t” and Spearman's rank correlation tests, and compared with data from previous studies. Results: Majority (104) drank 41–50 units of alcohol/week since 3–40 (mean: 20.01 ± 9.322) years. Generalized pruritus (odds ratio [OR]: 31.15, P < 0.001), xerosis (OR: 3.62, P = 0.008), and seborrheic dermatitis (OR: 12.26, P < 0.001) were significantly more common in cases than controls. Infections (73; 37.2%), eczemas (45; 22.9%), and generalized hyperpigmentation (28; 14.2%) were the major presenting complaints. Spider nevi, gynecomastia, and pellagroid dermatitis were present in 34 (17.3%), 19 (9.7%), and 8 (4.1%) respectively exclusively in cases only. Commonly seen systemic abnormalities were an alcoholic liver disease (45; 22.9%), diabetes mellitus (23; 11.7%), and peripheral neuropathy (19; 9.7%). Conclusion: Knowledge of cutaneous manifestations of chronic alcoholism could prompt in-depth history taking of alcohol intake, lead to specialist referral and thereby enable timely de-addiction, hopefully before serious adversities in the chronic alcoholics.


How to cite this article:
Sharma YK, Shukla P, Nayak R, Kothari P, Gupta A. Association of dermatoses with duration and quantum of alcohol intake: A comparative cross-sectional study.Indian J Dermatol 2017;62:184-190


How to cite this URL:
Sharma YK, Shukla P, Nayak R, Kothari P, Gupta A. Association of dermatoses with duration and quantum of alcohol intake: A comparative cross-sectional study. Indian J Dermatol [serial online] 2017 [cited 2020 Oct 20 ];62:184-190
Available from: https://www.e-ijd.org/article.asp?issn=0019-5154;year=2017;volume=62;issue=2;spage=184;epage=190;aulast=Sharma;type=0