Indian Journal of Dermatology
: 2013  |  Volume : 58  |  Issue : 2  |  Page : 93--100

Fixed-duration therapy in leprosy: Limitations and opportunities

Munisamy Malathi, Devinder Mohan Thappa 
 Department of Dermatology and STD, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India

Correspondence Address:
Devinder Mohan Thappa
Professor and Head, Department of Dermatology and STD, JIPMER, Pondicherry - 605 006

Leprosy has been considered a curable disease after the implementation of multidrug therapy (MDT), which has been proven to be safe and effective, by bringing about a significant change in the global and national scenario of leprosy by upgrading the control of leprosy to the next stage of eradication. Since its introduction, the MDT regimens for the treatment of leprosy have undergone several changes especially with regard to the duration of treatment. The advantages of shortened duration of treatment need to be balanced against the risk of relapse and a lot of controversies exist pertaining to this aspect. The fixed-duration (FD) therapy is not popular among academicians and private practitioners who prefer precise diagnosis and treatment with superior MDT regimens and for a longer duration. On the contrary, from a public health-care point of view, precise diagnosis and a longer treatment schedule are not cost effective and not feasible to be implemented in elimination programs. Hence, a fine balance needs to be maintained between achieving a cure for the patient and protecting the society at risk, and this review discusses the various limitations and opportunities of FD therapy with a note on the newer MDT regimens.

How to cite this article:
Malathi M, Thappa DM. Fixed-duration therapy in leprosy: Limitations and opportunities.Indian J Dermatol 2013;58:93-100

How to cite this URL:
Malathi M, Thappa DM. Fixed-duration therapy in leprosy: Limitations and opportunities. Indian J Dermatol [serial online] 2013 [cited 2021 Jul 30 ];58:93-100
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