Indian Journal of Dermatology
CASE REPORT
Year
: 2008  |  Volume : 53  |  Issue : 2  |  Page : 85--87

Rare presentation of Kyrle俟Q製 disease in siblings


Seethalakshmi Viswanathan1, Swati D Narurkar1, Aruna Rajpal2, NG Nagpur2, SS Avasare1 
1 Department of Pathology, KJ Somaiya Medical College, Sion, Ayurvihar, Mumbai, Maharashtra, India
2 Department of Dermatology, KJ Somaiya Medical College, Sion, Ayurvihar, Mumbai, Maharashtra, India

Correspondence Address:
Seethalakshmi Viswanathan
K-300, Mulund Darshan, Mulund Colony, Guru Gobind Singh Road, Mulund West, Mumbai - 400 082, Maharashtra
India

Background: Kyrle俟Q製 disease is a rare variant of primary perforating dermatosis. Its occurrence in a familial setting, especially in children, is extremely uncommon. Similar appearing skin lesions have been described in adults, secondary to metabolic disorders, infective agents as well as exposure to chemicals. We present a rare case of this genodermatosis in two siblings. Materials and Methods: Two siblings of a non-consanguineous marriage came with generalized discrete papular lesions with a central keratotic plug. All biochemical and serological investigations were within normal limits. Serial sections of the biopsy revealed typical epidermal invaginations filled with parakeratotic debris and perforation into the dermis with accompanying granulomatous reaction. Results and Conclusions: A careful history, detailed routine investigations and serial sections of the skin biopsy are required to demonstrate the typical morphology and stages of evolution of Kyrle俟Q製 disease. This helps to differentiate the rare primary Kyrle俟Q製 disease from other primary and secondary keratotic lesions. Due to the familial occurrence, screening of relatives of an index case is recommended.


How to cite this article:
Viswanathan S, Narurkar SD, Rajpal A, Nagpur N G, Avasare S S. Rare presentation of Kyrle's disease in siblings.Indian J Dermatol 2008;53:85-87


How to cite this URL:
Viswanathan S, Narurkar SD, Rajpal A, Nagpur N G, Avasare S S. Rare presentation of Kyrle's disease in siblings. Indian J Dermatol [serial online] 2008 [cited 2021 Sep 22 ];53:85-87
Available from: https://www.e-ijd.org/article.asp?issn=0019-5154;year=2008;volume=53;issue=2;spage=85;epage=87;aulast=Viswanathan;type=0