Indian Journal of Dermatology
CLINICOPATHOLOGICAL COLLOQUIUM
Year
: 2008  |  Volume : 53  |  Issue : 1  |  Page : 21--23

Clinicopathologic evaluation of mammary Paget俟Q製 disease


Naser Tayyebi Meibodi1, Vahid Mashayekhi Ghoyunlu2, Zari Javidi2, Yalda Nahidi2 
1 Department of Pathology, Imam-Reza Educational Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
2 Department of Dermatology, Imam-Reza Educational Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

Correspondence Address:
Naser Tayyebi Meibodi
Department of Pathology, Imam-Reza Educational Hospital, Mashhad University of Medical Sciences (MUMS), Mashhad
Iran

Mammary and extramammary Paget俟Q製 diseases are rare neoplasms of epidermis and mucosal epithelium. Due to their nonspecific and variable clinical view, they have differential diagnosis with eczema, melanoma, Bowen俟Q製 disease, etc. To the best of our knowledge, no such study has been performed in Iran regarding the prevalence, clinical aspects, underlying disease and pathological characteristics of these two diseases. In this study, we have evaluated the clinical and histopathological aspects of this disorder. Materials and Methods: In this retrospective study, all Paget俟Q製 biopsied samples referred to the Pathology Department of Imam-Reza hospital, Mashhad, since 1984 till 2004 were evaluated. Collected data were analyzed by descriptive statistical methods. Results: Among 98925 specimens, there were 29 cases of Paget俟Q製 disease. All cases were married women suffering from mammary Paget. The mean age was 53 11 years. Left and right breast involvement was observed in 17 and 12 cases, all unilateral. The most common clinical view was ulcerated (27%) and then erythematosus exudative plaques. More than 50% of patients were symptomatic. Most common symptoms were itching, pain and burning. The exclusive underlying pathological diagnosis was ductal carcinoma (55%). Discussion: In most cases, the clinical view of mammary Paget俟Q製 disease was helpful. Unilateral ulcerated plaque was the most common clinical sign. Majority of the accompanying pathology was ductal carcinoma. We had no cases of extramammary Paget俟Q製 disease in our study.


How to cite this article:
Meibodi NT, Ghoyunlu VM, Javidi Z, Nahidi Y. Clinicopathologic evaluation of mammary Paget's disease.Indian J Dermatol 2008;53:21-23


How to cite this URL:
Meibodi NT, Ghoyunlu VM, Javidi Z, Nahidi Y. Clinicopathologic evaluation of mammary Paget's disease. Indian J Dermatol [serial online] 2008 [cited 2021 Apr 11 ];53:21-23
Available from: https://www.e-ijd.org/article.asp?issn=0019-5154;year=2008;volume=53;issue=1;spage=21;epage=23;aulast=Meibodi;type=0