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Year : 2020  |  Volume : 65  |  Issue : 4  |  Page : 315
Three sequential lymphomatous tumors in a patient - Reader's question

Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

Date of Web Publication11-Jun-2020

Correspondence Address:
Mahmood Dhahir Al-Mendalawi
Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijd.IJD_487_18

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How to cite this article:
Al-Mendalawi MD. Three sequential lymphomatous tumors in a patient - Reader's question. Indian J Dermatol 2020;65:315

How to cite this URL:
Al-Mendalawi MD. Three sequential lymphomatous tumors in a patient - Reader's question. Indian J Dermatol [serial online] 2020 [cited 2021 Sep 18];65:315. Available from: https://www.e-ijd.org/text.asp?2020/65/4/315/286402


In their interesting case report, Choi etal.[1] described a series of lymphomas, namely, Hodgkin's lymphoma, mycosis fungoides, and marginal zone B-cell lymphoma/chronic lymphomatous leukemia in a Singaporean patient. In view of the rarity of sequential tumors to develop in a patient, I presume that the authors ought to take into consideration defective immune status in the studied patient. Among defective immune states, infection with human immunodeficiency virus (HIV) is the leading. My presumption is based on the following point. It is obvious that immunocompromised patients are more susceptible to various types of tumors compared to healthy controls. The increased susceptibility has been attributed to different factors, namely impaired immunity, co-infection with oncogenic viruses, and life extension due to the use of antiretroviral treatment.[2] In Singapore, HIV infection is an important health hazard. The recently published data pointed out to 0.2% adult HIV prevalence rate.[3] Regrettably, the HIV status of the studied patient was not determined. Hence, arranging for HIV testing through the diagnostic set of CD4 lymphocyte count and viral load estimations were solicited. If these tests were to disclose HIV reactivity, the case in question could be truly considered a novel case report in Singapore. This is because sequential tumors in a HIV-positive patient has been rarely reported in the world literature.[4]

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   References Top

Choi E, Yang S, Tan KB, Aw D, Chandran NS. Three sequential lymphomatous tumors in a patient. Indian J Dermatol 2018;63:443-4.  Back to cited text no. 1
[PUBMED]  [Full text]  
Valencia Ortega ME. Malignancies and infection due to the human immunodeficiency virus. Are these emerging diseases? Rev Clin Esp 2018;218:149-55.  Back to cited text no. 2
UNAIDS. Country Factsheets, Singapore 2017. HIV and AIDS Estimates. Available from: http://www.unaids.org/en/regionscountries/countries/singapore. [Last accessed on 2018 Sep 20].  Back to cited text no. 3
Skopelitis E, Panayiotakopoulos GD, Kontos AN, Androulaki A, Hatzianastassiou D, Hatzimanolis E, et al. Sequential development of triple malignancy in an HIV-positive patient. J Chemother 2003;15:97-8.  Back to cited text no. 4


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