Indian Journal of Dermatology
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  Official organ of AADV
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Year : 2019  |  Volume : 64  |  Issue : 4  |  Page : 324-327

Follicular graft-versus-host disease: A rare manifestation in a patient with the overlap subtype of chronic graft-versus-host disease

1 Department of Dermatology, Taipei Veterans General Hospital; Department of Dermatology, National Yang-Ming University, Taipei, Taiwan
2 Department of Dermatology, Taipei Veterans General Hospital; Department of Dermatology, National Yang-Ming University; Department of Dermatology, National Defense Medical Center, Taipei, Taiwan

Correspondence Address:
Han-Nan Liu
Department of Dermatology, Taipei Veterans General Hospital, 201, Section 2, Shih-Pai Road, 112, Taipei
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijd.IJD_412_18

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Graft-versus-host disease (GVHD) is a frequent and potentially life-threatening complication of hematopoietic stem cell transplantation (HSCT). Although skin involvement is common, generalized follicular eruption as the major clinical manifestation is rare. However, it is important for clinicians to recognize it at the earliest to initiate an appropriate therapy. We report a case of a patient with multiple myeloma who developed extensive hyperkeratotic, lichenoid folliculocentric papules with perifollicular erythema on day 53 following an allogeneic HSCT. The overall clinical and histological findings were consistent with the overlap subtype of chronic follicular GVHD.

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