Indian Journal of Dermatology
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Year : 2018  |  Volume : 63  |  Issue : 3  |  Page : 261-263

Reed's syndrome

1 Department of Dermatovenereology, Hospital De Braga, Braga, Portugal
2 Department of Surgical Pathology, Hospital De Braga, Braga, Portugal

Correspondence Address:
Dr. Filipa Tavares Almeida
Rua Humberto Delgado 555, 4445-450 Ermesinde, Porto
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijd.IJD_69_18

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Multiple cutaneous and uterine leiomyomatosis (MCUL), also known as Reed's syndrome, is a rare genodermatosis, with an autosomal dominant pattern of inheritance. It results from a germline heterozygous mutation of fumarate hydratase gene, that is classified as a tumor suppressor gene. Hereditary leiomyomatosis and renal cell cancer is characterized by the association of MCUL with renal cell carcinoma. We report a case of a 57-year-old woman, with multiple cutaneous leiomyomas as the presenting sign of Reed's syndrome.

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