| ORIGINAL ARTICLE |
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| Year : 2018 | Volume
: 63
| Issue : 2 | Page : 155-159 |
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Antimicrobial susceptibility of tinea capitis in children from Egypt
Reham William Doss1, Abdel-Aziz El-Rifaie1, Nagla Radi2, Aya Yehia El-Sherif1
1 Department of Dermatology, Faculty of Medicine, Beni-Suef University, Beni Suef, Egypt
2 Department of Microbiology and Immunology, Faculty of Medicine, Beni-Suef University, Beni Suef, Egypt
Correspondence Address:
Dr. Reham William Doss
Department of Dermatology, Faculty of Medicine, Beni-Suef University, Mohammed Hassan Street, Beni Suef 62111
Egypt
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijd.IJD_519_17
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Background: Dermatophytic fungi of genera Trichophyton and Microsporum are the most important fungal species causing tinea capitis. Choice of treatment for tinea capitis is determined by the species of fungus. Aim: The aim of the study was to investigate the most prevalent fungal species causing tinea capitis in children from Egypt and the most useful antifungal agent for treatment. Patients and Methods: A total of 100 patients diagnosed clinically with tinea capitis were included in the study. Samples were collected and sent to the microbiology and immunology laboratory for sample processing and fungal identification by routine laboratory techniques. A study of antifungal susceptibility to chosen antifungal medications (fluconazole, ketoconazole, clotrimazole, miconazole, amphotericin, caspofungin, itraconazole, terbinafine, and griseofulvin) was done by minimum inhibitory concentration technique. Results: Our analysis revealed that Microsporum canis is the most commonly isolated strain. Amphotericin was the most effective antifungal agent followed by terbinafine. The most sensitive strain to fluconazole and griseofulvin is Microsporum gypseum, while Microsporum audouinii was mostly responsive to terbinafine. Conclusion: Identification and evaluation of the antifungal susceptibility of the pathogenic species in a certain geographic region is important to achieve a good clinical response.
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