IJD
Indian Journal of Dermatology
  Publication of IADVL, WB
  Official organ of AADV
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E-IJD® - CASE REPORT
Year : 2016  |  Volume : 61  |  Issue : 6  |  Page : 700

A rare case of juvenile systemic lupus erythematosus with disseminated histoplasmosis


Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India

Correspondence Address:
Piyabi Sarkar
Ganapati Enclave, 117A, Santosh Roy Road, Block - A/1, Flat No. 304, Kolkata - 700 008, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.193710

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Histoplasmosis is a systemic fungal infection caused by dimorphic fungus, Histoplasma capsulatum. Immunocompetent individuals usually have self-limiting or localized disease whereas immunocompromised individuals develop disseminated disease. The occurrence of progressive disseminated histoplasmosis in juvenile systemic lupus erythematosus is extremely rare with only one reported case in literature showing such association. Therefore, we report a case of severe opportunistic fungal infection caused by Histoplasma in a 13-year-old girl who was diagnosed with juvenile lupus erythematosus, subsequently developed septic shock and died of the disease despite of aggressive antifungal therapy.


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