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Indian Journal of Dermatology
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THERAPEUTIC ROUND
Year : 2015  |  Volume : 60  |  Issue : 5  |  Page : 470-472

Successful repigmentation of vitiligo after allogeneic bone marrow transplantation for Hodgkin's lymphoma by autologous noncultured melanocyte-keratinocyte transplantation


1 Department of Dermatology, Second People's Hospital of Liu An, Anhui, China
2 Department of Dermatology, Affiliated Hangzhou Clinical College, Anhui Medical University, Hangzhou, China
3 Third People's Hospital of Hangzhou, Hangzhou Institute of Dermatology and Venereology, Hangzhou, China

Correspondence Address:
Ai-e Xu
38 Xi Hu Da Dao, Hangzhou, Zhejiang, 310009
China
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Source of Support: This study was supported by the National Natural Science Foundation of China (grant no. 81271758) and the Co-construction Project of Ministry of Health and Zhejiang Province (grant no. WKJ2012-2-036), Conflict of Interest: None


DOI: 10.4103/0019-5154.164364

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The treatment of vitiligo is derisory since the pathogenesis of vitiligo is not clear at present. Most conservative treatments are difficult to approach satisfactory therapy. So transplantation is the only way left when the disease becomes insensitive to those conservative treatments. Here we describe an 18-year-old patient who developed vitiligo, which was triggered by graft-versus-host disease after a allogeneic bone marrow transplantation for the treatment of Hodgkin's lymphoma from his sister. In the following treatment to vitiligo, the patient successfully performed the transplantation of autologous uncultured melanocyte on the premise of poor reaction to other conservative methods. We infer that transplantation can be a treatment of the vitiligo after allogeneic bone marrow transplantation.


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