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Year : 2015  |  Volume : 60  |  Issue : 3  |  Page : 325
Recurrent and diffuse eczema with severe itch and peripheral eosinophilia in healthy middle aged woman

Department of Dermatology, S Nijlingappa Medical College, Bagalkot, India

Date of Web Publication6-May-2015

Correspondence Address:
Mahesh Unni
Department of Dermatology, S Nijlingappa Medical College, Bagalkot 587102, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.156490

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How to cite this article:
Unni M, Ankad B, Naidu V, Sudakar K M. Recurrent and diffuse eczema with severe itch and peripheral eosinophilia in healthy middle aged woman. Indian J Dermatol 2015;60:325

How to cite this URL:
Unni M, Ankad B, Naidu V, Sudakar K M. Recurrent and diffuse eczema with severe itch and peripheral eosinophilia in healthy middle aged woman. Indian J Dermatol [serial online] 2015 [cited 2021 Sep 22];60:325. Available from:

A 45-year-old woman presented with generalized itchy skin lesions particularly more on extremities and back. Lesions were present since past 3 years and were not related to injury, insect bites or drug intake. There was no history of similar complaints in her family.

On examination, there were multiple, hyperpigmented patches and plaques varying from 3 x 10 to 5 x 15 cms in size with many excoriated papules and crusts [Figure 1] and [Figure 2]. The systemic examination was unremarkable and peripheral blood examination showed high eosinophilic count of 40% and absolute count of 6640. Chest X-ray was normal as well as renal and liver function tests were normal. For clinical diagnosis, a punch biopsy was taken from the back and histopathological report showed changes as shown in [Figure 3] and [Figure 4].

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   References Top

Wells GC. Recurring granulomatous dermatitis with eosinophilia.Trans St Johns Hosp Dermatol Soc 1971;57:46-56.  Back to cited text no. 1
Wells GC, Smith NP. Eosinophilic cellulitis. Br J Dermatol 1979; 100:101-9.  Back to cited text no. 2
Anderson CR, Jenkins D, Tron V, Prendiville JS. Wells syndrome in childhood: Case report and review of the literature. J Am Acad Dermatol 1995;33:857-64.  Back to cited text no. 3
Winfield H, Lain E, Horn T, Hoskyn J. Eosinophilic cellulitis-like reaction to subcutaneous etanercept injection. Arch Dermatol 2006;142:218-20.  Back to cited text no. 4
Boura P, Sarantopoulos A, Lefaki I, Skendros P. Eosinophilic cellulitis as cutenous reaction to the administration of adalimumab. Ann Rheum Dis 2006;65:839-40.  Back to cited text no. 5
Wood C, Miller AC, Jacobs A, Hart R, Nickoloff BJ. Eosinophilic infiltration with flame figures. Am J Dermatopathol 1986;8:186-93.  Back to cited text no. 6
Simon JC. Diseases with Eoisnophilia. In: Braun-Falco O, Burgdorf WH, Plewig G, Wolff HH, Landthaler M, editors.Dermatology. 3 rd ed.Germany: Heidelberg; 2009. p. 566-7.  Back to cited text no. 7
Johan W, White CT Jr. Hypersensitivity and Miscellaneous inflammatory Disorders. In: Moschella SC, Hurley HJ, editors.Dermatology. 2 nd ed. Philadelphia: WB Sunders, 1985. p. 489-90.  Back to cited text no. 8
Herr H, Koh JK. Eosinophilic Cellulitis successfully treated with low-dose Cyclosporine. J Korean Med Sci 2001;16:664-8.  Back to cited text no. 9
Sharma PK, Gautam RK, Sharma AK. Eosinophilic cellulitis-A case study and management with griseofulvin. Indian J Dermatol Venerol Leprol 1995;61:163-4.  Back to cited text no. 10
Chung CL, Cusack CA. Wells syndrome: An enigmatic and therapeutically challenging disease. J Drugs in Dermatol 2006; 78:525-7.  Back to cited text no. 11


  [Figure 1], [Figure 2], [Figure 3], [Figure 4]


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