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Year : 2015  |  Volume : 60  |  Issue : 3  |  Page : 316-318
Annular erythematous plaques on the face, trunk and extremities of an infant


1 Department of Dermatology, Pathology, Research Center for Skin Diseases and Cutaneous Leishmanaisis, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2 Department of Pathology, Research Center for Skin Diseases and Cutaneous Leishmanaisis, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Date of Web Publication6-May-2015

Correspondence Address:
Naser Tayyebi Meibodi
Department of Pathology, Research Center for Skin Diseases and Cutaneous Leishmanaisis, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.156411

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How to cite this article:
Nahidi Y, Meibodi NT, Javidi Z, Moghimi HR. Annular erythematous plaques on the face, trunk and extremities of an infant. Indian J Dermatol 2015;60:316-8

How to cite this URL:
Nahidi Y, Meibodi NT, Javidi Z, Moghimi HR. Annular erythematous plaques on the face, trunk and extremities of an infant. Indian J Dermatol [serial online] 2015 [cited 2021 Jul 29];60:316-8. Available from: https://www.e-ijd.org/text.asp?2015/60/3/316/156411


The patient is a 6-month-old infant who presented with annular erythematous plaques with mild scaling on the face, especially forehead and around the eyes, gradually spreading to the neck, trunk and extremities since 4 months ago [Figure 1], [Figure 2], [Figure 3]. Its general health has been good and he had no problems at birth. The patient has been the first child of the family, with a history of pain in the joints of hand in the mother from about 3 years ago without citing a specific diagnosis. Skin biopsy was taken from the infant, which showed vacuolar changes in the epithelial basement membrane in dermoepidermal junction and in the epithelial junction of the appendages with necrotic keratinocytes, perivascular and periadnexal infiltrates with lymphocyte predominance and precipitation of dermal mucin [Figure 4] and [Figure 5].
Figure 1: Annular erythematous plaques on the face

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Figure 2: Annular erythematous plaques on the trunk

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Figure 3: Annular erythematous plaques on the lower extremities

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Figure 4: Hydropic degeneration of basal keratinocytes, dermal edema and a superficial lymphohistiocytic chronic inflammatory cell infiltrate (H and E, ×40)

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Figure 5: Basal vacuolar change with occasional civatte bodies (H and E, ×100 and ×400)

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   References Top

1.
Wisuthsarewong W, Soongswang J, Chantorn R. Neonatal lupus erythematosus: Clinical character, investigation, and outcome. PediatrDermatol 2011;28:115-21.  Back to cited text no. 1
    
2.
Perez MF, Torres ME, Buján MM, Lanoël A, Cervini AB, Pierini AM. Neonatal lupus erythematosus: A report of four cases. An Bras Dermatol 2011;86:347-51.  Back to cited text no. 2
    
3.
Lee LA. Neonatal lupus erythematosus: Clinical findings and pathogenesis. J Investig Dermatol Symp Proc 2004;9:52-6.  Back to cited text no. 3
    
4.
Lee LA. Cutaneous lupus in infancy and childhood. Lupus 2010;19:1112-7.  Back to cited text no. 4
    
5.
Lee LA. Neonatal lupus: Clinical features and management. Paediatr Drugs 2004;6:71-8.  Back to cited text no. 5
    
6.
Neiman AR, Lee LA, Weston WL, Buyon JP. Cutaneous manifestations of neonatal lupus without heart block: Characteristics of mothers and children enrolled in a national registry. J Pediatr 2000;137:674-80.  Back to cited text no. 6
    
7.
Peñate Y, Guillermo N, Rodríguez J, Hernández-Machín B, Montenegro T, Afonso JL, Borrego L. Histopathologic characteristics of neonatal cutaneous lupus erythematosus: Description of five cases and literature review. JCutanPathol 2009;36:660-7.  Back to cited text no. 7
    
8.
Silverman E, Jaeggi E. Non-cardiac manifestations of neonatal lupus erythematosus. Scand J Immunol 2010;72:223-5.  Back to cited text no. 8
    


    Figures

  [Figure 1], [Figure 2], [Figure 3], [Figure 4], [Figure 5]



 

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