Indian Journal of Dermatology
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Year : 2015  |  Volume : 60  |  Issue : 2  |  Page : 217

Familial atypical multiple mole melanoma syndrome in an adult Indian male-case report and literature review

1 From the Department of Surgery, Goa Medical College, Bambolim, Goa, India
2 Goa Medical College, Bambolim, Goa, India

Correspondence Address:
Dr. Radhika C G Raj
Associate Professor of Surgery, Goa Medical College, Bambolim, Goa - 403 202
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.152585

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Familial atypical multiple mole melanoma syndrome (FAMMMS) is an autosomal dominant genodermatosis characterized by multiple melanocytic nevi, usually more than 50, and a family history of melanoma. It is known to be associated with carcinoma of pancreas and other malignancies involving gastrointestinal tract, breast, lung, larynx, and skin in the kindred. There is no published report of FAMMMS in dark-skinned individuals. We report a case of FAMMMS in a dark-skinned adult Indian male, who had multiple extensive nevi all over the body and oral mucosa; associated with malignant melanoma, squamous cell carcinoma (Marjolin's ulcer), and carcinoma of pancreas. His father had died of carcinoma of lung and his sister had a partial phenotypic expression. The clinical presentation of the case is discussed with review of literature.

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