Indian Journal of Dermatology
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Year : 2015  |  Volume : 60  |  Issue : 2  |  Page : 216

Poikiloderma vasculare atrophicans: A distinct clinical entity?

From the Department of Dermatology, Venereology and Leprosy, Dr. RP Govt. Medical College, Kangra (Tanda), Himachal Pradesh, India

Correspondence Address:
Dr. Vikram K Mahajan
Department of Dermatology, Venereology and Leprosy, Dr. RP Govt Medical College, zangra (Tanda) 176 001, Himachal Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.152566

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This paper describes a typical case of poikiloderma vasculare atrophicans (PVA) in a 48-year-old female. Histologically, the features were suggestive of PVA with the absence of Pautrier's microabscess or atypical lymphoid cells. The biopsy specimen was positive for cluster of differentiation (CD) 8 on immunohistochemical staining. Its exact pathogenesis remains obscure, and it remains unclear whether PVA actually is mycosis fungoides (MF), a forme fruste of MF, or a distinct and benign dermatosis with CD8+ phenotype that can perhaps be labeled as PVA. However, it has a long benign clinical course without progression to tumor stage of MF in most cases, and its status within the spectrum of cutaneous T-cell lymphoma remains poorly understood. Yet it is imperative to distinguish PVA from poikilodermic MF.

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