Indian Journal of Dermatology
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Year : 2015  |  Volume : 60  |  Issue : 2  |  Page : 215

Rowell's syndrome to ds-dna negative lupus nephritis: A yet unreported progression

Department of Skin and VD, MGM Medical College, Navi Mumbai, India

Correspondence Address:
Mayur R Bhobe
SPARC, Behind Chowgule College, Cupangale, Fatorda, Salcete, Goa - 403602
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.152604

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Rowell's syndrome is now identified as a subtype of subacute lupus erythematosus (LE) with erythema multiforme-like skin lesions, positive serum rheumatoid factor, anti-Ro La positivity and speckled pattern of antinuclear antibodies. Here we describe a case of Rowell's syndrome in an 18-year-old female who was found to be ds-DNA negative, who later progressed to develop stage V lupus nephritis (LN) over a course of 4 months. Although extremely rare, most cases of LN are drug induced. Of only seven cases of non-drug induced LN with negative dsDNA, none had cutaneous involvement. Ours was a unique case of progression of Rowells syndrome to ds-DNA negative LN.

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