Indian Journal of Dermatology
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Year : 2014  |  Volume : 59  |  Issue : 2  |  Page : 210

Rare case of phenytoin induced acute generalized exanthematous pustulosis with cerebellar syndrome

1 Department of Medicine, Government Medical College and Hospital, Nagpur, India
2 Department of Skin and V. D., Government Medical College and Hospital, Nagpur, India

Correspondence Address:
Pravin U Shingade
Department of Medicine, Government Medical College and Hospital, Nagpur
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.127715

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Acute generalized exanthematous pustulosis (AGEP) is a rare drug induced cutaneous hypersensitivity reaction characterized by sudden onset of fever with sterile pustules overlying an erythematous skin occurring all over the body. The offending drugs are usually B-lactams and macrolides.Among anticonvulsants carbamazepine and Phenobarbital are commonly associated with AGEP. Only one case of phenytoin induced AGEP has been reported in literature. We present a rare case of AGEP with cerebellar syndrome occurring after receiving loading dose of phenytoin.

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