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Table of Contents 
Year : 2013  |  Volume : 58  |  Issue : 6  |  Page : 490-491
Asymptomatic peri-orifical papular lesions in a child

1 Department of Dermatology, Seth G.S. Medical College and K.E.M. Hospital, Mumbai, Maharashtra, India
2 Department of Dermatology and Consultant Dermatopathologist, Seth G.S. Medical College and K.E.M. Hospital, Mumbai, Maharashtra, India

Date of Web Publication17-Oct-2013

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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.119969

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How to cite this article:
Doshi BR, Haldar SS, Khopkar US. Asymptomatic peri-orifical papular lesions in a child. Indian J Dermatol 2013;58:490-1

How to cite this URL:
Doshi BR, Haldar SS, Khopkar US. Asymptomatic peri-orifical papular lesions in a child. Indian J Dermatol [serial online] 2013 [cited 2021 Jul 23];58:490-1. Available from: https://www.e-ijd.org/text.asp?2013/58/6/490/119969

   Case Presentation Top

A six-year-old boy presented with a one month history of asymptomatic raised lesions around the mouth, eyes and chin. There was no history of contact allergens. The remainder of his medical history was unremarkable. Cutaneous examination revealed multiple tiny flesh-colored as well as erythematous papules, some of which were shiny and distributed around the mouth, nose, eyes and chin [Figure 1] with a tendency to become confluent at a few places. Results of the examination of the rest of the skin and mucous membranes were completely normal. Chest roentgenogram was normal. Findings of the skin biopsy specimen taken from a flesh colored papule above the chin is shown in [Figure 2] and [Figure 3]. The complete blood cell count and blood chemistry panel were within normal limits. Erythrocyte sedimentation rate was 25 mm at the end of one hour. Mantoux test for tuberculosis was negative.
Figure 1: Multiple skin colored to erythematous papules over peri-occular, perinasal, peri-oral region and chin

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Figure 2: H and E stained skin biopsy section on (×5) magnification showing circumscribed perifollicular non-caseating epithelioid cell granulomas with few surrounding lymphocytes

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Figure 3: H and E stained skin biopsy section on (×20) magnification showing perifollicular epithelioid cell granulomas along with scant lymphocytic infiltrate

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   Question Top

   What is your diagnosis? Top

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   References Top

1.Gianotti F, Ermacora E, Bennelli MG, Caputo R. Particuliere dermatitie periorale infantile. Observations sur 5 cas. Bull Soc Fr Dermatol Syphiligr 1970;77:341.  Back to cited text no. 1
2.Marten RH, Presbury DG, Adamson JE, Cardell BS. An unusual papular and acneiform facial eruption in the negro child. Br J Dermatol 1974;91:435-8.  Back to cited text no. 2
3.Frieden IJ, Prose NS, Fletcher V, Turner ML. Granulomatous perioral dermatitis in children. Arch Dermatol 1989;125:369-73.  Back to cited text no. 3
4.Williams HC, Ashworth J, Pembroke AC, Breathnach SM. FACE-facial Afro-Carribean childhood eruption. Clin Exp Dermatol 1990;15:163-6.  Back to cited text no. 4
5.Knautz MA, Lesher JL Jr. Childhood granulomatous periorificial dermatitis. Pediatr Dermatol 1996;13:131-4.  Back to cited text no. 5
6.Fisher AA. Sarcoid-like periocular dermatitis due to strong topical corticosteroids: Prompt response to treatment with tetracycline. Cutis 1987;40:95-6.  Back to cited text no. 6
7.Antony FC, Buckley DA, Russel-Jones R. Childhood granulomatous periorificial dermatitis in an Asian girl: A variant of sarcoid? Clin Exp Dermatol 2002;27:275-6.  Back to cited text no. 7
8.Hansen KK, McTigue MK, Esterly NB. Multiple facial, neck, upper trunk papules in a black child. Childhood granulomatous perioral dermatitis with involvement of the neck and upper trunk. Arch Dermatol 1992;128:1396-7.  Back to cited text no. 8
9.Misago N, Nakafusa J, Narisawa Y. Childhood granulomatous periorificial dermatitis: Lupus miliaris disseminatus faciei in children? J Eur Acad Dermatol Venereol 2005;19:470-3.  Back to cited text no. 9
10.Choi YL, Lee KJ, Cho HJ, Kim WS, Lee HJ, Yang JM, et al. Case of childhood granulomatous periorificial dermatitis in a Korean boy treated by oral erythromycin. J Dermatol 2006;33:806-8.  Back to cited text no. 10


  [Figure 1], [Figure 2], [Figure 3]


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