Indian Journal of Dermatology
  Publication of IADVL, WB
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Year : 2013  |  Volume : 58  |  Issue : 3  |  Page : 243

Microsporum canis infection mimics pemphigus erythematosus

1 Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
2 Department of Dermatology, Kanazawa Medical University, Kanazawa, Japan

Correspondence Address:
Hiroo Amano
Department of Dermatology, 3 39 22 Showa machi, Maebashi, Gunma 371 8511
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.110866

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We report a 55-year-old Japanese woman with a two-month history of multiple pruritic erythema and erosion on her face and neck. Based on the clinical appearance, we initially diagnosed her as having pemphigus erythematosus. However, the results of a histopathological examination and a direct immunofluorescence study did not support the initial diagnosis. Additionally, anti-desmoglein 1 and 3 antibodies were all negative. Subsequently, a microscopic examination of scales revealed filaments of fungi and a fungal culture was negative for macroconidium. Using molecular biology techniques, we identified the fungus as Microsporum canis, which causes a zoonotic infection. The immune reaction to the fungi could be drastic and therefore, the eruption sometimes displays atypical clinical manifestations.

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