Indian Journal of Dermatology
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Table of Contents 
Year : 2012  |  Volume : 57  |  Issue : 3  |  Page : 244-245
Authors' reply

1 Department of DVL, PESIMSR, Kuppam, Andhra Pradesh, India
2 Department of Skin and STD, Mandya Institute of Medical Sciences, Mandya, Karnataka, India

Date of Web Publication16-May-2012

Correspondence Address:
Raghunatha R Reddy
Department of DVL, PESIMSR, Kuppam, Andhra Pradesh
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Source of Support: None, Conflict of Interest: None

PMID: 22707789

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How to cite this article:
Reddy RR, Shashi Kumar B M, Harish M R. Authors' reply. Indian J Dermatol 2012;57:244-5

How to cite this URL:
Reddy RR, Shashi Kumar B M, Harish M R. Authors' reply. Indian J Dermatol [serial online] 2012 [cited 2023 Sep 29];57:244-5. Available from:


This is with reference to your letter commenting on the case report titled 'Cutaneous sarcoidosis - A great masquerader: A report of three interesting cases,' for case 1 and case 3. We appreciate the suggestion of considering Acne agminata or lupus miliaris disseminatus faciei (LMDF), both clinically and histpathologically, but the reasons to omit this are as follows:

  1. It differs clinically, because the lesions are smooth dome-shaped papules without any necrotic center and there were no scars, either superficial or deep, suggestive of the healed lesions of LMDF, as the lesions of LMDF last for months and heal with scarring. [1]
  2. Lupus miliaris disseminatus faciei is considered as one of the invisible dermatoses, for which the diagnosis is mainly histopathological. We were waiting for the histopathology report to consider the same on arrival of the histopathology diagnosis, but for the fact that the granulomas were clearly and distinctively naked epitheloid granulomas and there was no necrosis or caseation; also the pathologist had performed the Reticulin stain as per our suggestion at the time of request and that was in favor of sarcoidosis. As you have rightly pointed out, sarcoidal granulomas could be the first stage of histological presentation of LMDF. [2] We would like to inform you that the lesion biopsied was nearly one year old, by which time probably if it were to be LMDF, it would have developed necrosis at least histologically.
  3. Also, the elevated serum Angiotensin converting enzyme level was a contributory finding for the diagnosis of sarcoidosis.
By this we conclude by stating that at all levels, clinical, investigative, histopathological, and special stain, the diagnosis was very close to sarcoidisis, and we could not find good supportive points for the diagnosis of LMDF.

We deeply appreciate your communication.

   References Top

1.Kumano K, Tani M, Murata T. Dapsone in the treatment of military lupus of the face. Br J Dermatol 1983;109:57-62.  Back to cited text no. 1
2.Ioffreda MD. Inflammatory diseases of hair follicle, sweat glands, and cartilage. In: Elder DE, editor-in-chief. Lever's histopathology of the skin. 10 th ed. Philadelphia: Lippincott Williams and Wilkins; 2009. p. 459-501.  Back to cited text no. 2


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