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Table of Contents 
Year : 2011  |  Volume : 56  |  Issue : 6  |  Page : 776-777
Mulberry like growth in the right ear

Department of Dermatology, Kasturba Medical College, Manipal, Manipal University, Udupi District, Karnataka, India

Date of Web Publication14-Jan-2012

Correspondence Address:
Mohan H Kudur
Department of Dermatology, Kasturba Medical College, Manipal, Manipal University, Udupi District, Karnataka - 576 104
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.91856

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How to cite this article:
Kudur MH. Mulberry like growth in the right ear. Indian J Dermatol 2011;56:776-7

How to cite this URL:
Kudur MH. Mulberry like growth in the right ear. Indian J Dermatol [serial online] 2011 [cited 2021 Mar 3];56:776-7. Available from: https://www.e-ijd.org/text.asp?2011/56/6/776/91856

A 68 year old male agriculturist presented with asymptomatic growth over his right ear for the past three years. The growth was insidious in onset and started as a small firm pigmented papule three years back. The lesion was aymptomatic and gradually increased in size. He gives history of occasional bleeding on touch. No history of similar skin lesion in the past or in family members. No history of any type of ear trauma or ear surgery in the past. Examination revealed 3 × 4 cm, mulberry like pigmented growth [Figure 1], soft to firm in consistency, mobile with no tenderness on palpation seen in the groove between helix and anti-helix of right ear. Excission biopsy was done and histopathology of the tumor showed hyperkeratosis, parakeratosis, acanthosis and papillomatosis with sharp horizontal demarcation from the dermis. The epidermal cells are composed of squamous and basaloid cells with abundant melanin pigment and keratohyaline granules. Squamous eddies and several horncysts are seen [Figure 2] and [Figure 3]. Non-specific lymphocyitc inflammatory infiltrate was seen in upper dermis.
Figure 1: Mulberry like pigmented growth seen over right ear

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Figure 2: Histopathology shows hyperkeratosis, parakeratosis, acanthosis, papillomatosis with multiple squamous eddies and horncysts seen. Dermis showing non-specific inflammatory infiltrate seen (H and E stain, 10×)

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Figure 3: Higher magnification showing squamous eddies and horncysts (H and E stain, 40×)

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   References Top

1.Groves RW, Allen MH, MacDonald DM. Abnormal expression of epidermal growth factor receptor in cutaneous epithelial tumours. J Cutan Pathol 1992;19:66-72.   Back to cited text no. 1
2.Nanney LB, Ellis DL, Levine J, King LE. Epidermal growth factor receptors in idiopathic and virally induced skin diseases. Am J Pathol 1992;140:915-25.   Back to cited text no. 2
3.Nakagawa K, Yamamura K, Maeda S, Ichihashi M. bcl-2 expression in epidermal keratinocytic diseases. Cancer 1994;74:1720-4.   Back to cited text no. 3
4.Hafner C, Hartmann A, Vogt T. FGFR3 mutations in epidermal nevi and seborrheic keratoses: lessons from urothelium and skin. J Invest Dermatol 2007;127:1572-3.   Back to cited text no. 4
5.Hafner C, van Oers JM, Hartmann A, Landthaler M, Stoehr R, Blaszyk H, et al. High frequency of FGFR3 mutations in adenoid seborrheic keratoses. J Invest Dermatol 2006;126:2404-7.   Back to cited text no. 5
6.Hafner C, Hartmann A, Real FX, Hofstaedter F, Landthaler M, Vogt T. Spectrum of FGFR3 mutations in multiple intraindividual seborrheic keratoses. J Invest Dermatol 2007;127:1883-5.   Back to cited text no. 6
7.Mehregan AH. Inverted follicular keratosis. Arch Dermatol 1964;89:229-35.  Back to cited text no. 7
8.Kossard S, Berman A, Winkelmann RK. Seborrheic keratoses and trichostasis spinulosa. J Cutan Pathol 1979;6:492-5.  Back to cited text no. 8
9.Konishi E, Nakashima Y, Manabe T, Mazaki T, Wada Y. Irritated seborrheic keratosis of the external ear canal. Pathol Int 2003;53:622-6.   Back to cited text no. 9
10. Lee JP, Kim YJ. A case of irritated seborrheic keratosis associated with a previous incision site. Korean J Ophthalmol 2010;24:173-4.  Back to cited text no. 10


  [Figure 1], [Figure 2], [Figure 3]


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