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Indian Journal of Dermatology
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CASE REPORT
Year : 2011  |  Volume : 56  |  Issue : 6  |  Page : 718-721

Churg-strauss syndrome


1 Consultant Pulmonologist, AMRI Hospitals, Dhakuria, Kolkata, India
2 Consultant Hematologist, AMRI Hospitals, Dhakuria, Kolkata, India
3 Consultant Dermatologist, AMRI Hospitals, Dhakuria, Kolkata, India

Correspondence Address:
Subhasish Ghosh
Consultant Pulmonologist, AMRI Hospitals, P - 4 & 5, CIT Scheme, LXXII Block - A Gariahat Road, Dhakuria, Kolkata
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.91836

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Churg-Strauss syndrome (CSS) is a rare granulomatous necrotizing small vessel vasculitis characterized by the presence of asthma, sinusitis, and hypereosinophilia. The cause of this allergic angiitis and granulomatosis is unknown. Other common manifestations are pulmonary infiltrates, skin, gastrointestinal, and cardiovascular involvement. No data have been reported regarding the role of immune complexes or cell mediated mechanisms in this disease, although autoimmunity is evident with the presence hypergammaglobulinemia, increased levels of IgE and Antineutrophil cytoplasmic antibody (positive in 40%). We report the case of a 27-year-old lady presenting with painful swelling of predominantly lower limbs with extensive vesicles and ecchymotic patches and fever shortly after stopping systemic steroids taken for a prolonged duration (2002--2010). The aim of this case report is to point to the possibility of CSS in patients presenting with extensive skin lesions masquerading as Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Syndrome (SJS/TENS).


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