Indian Journal of Dermatology
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Table of Contents 
Year : 2011  |  Volume : 56  |  Issue : 2  |  Page : 230-231
Facial nodule in a 34-year-old man

1 Department of Dermatology, Safdarjang Hospital and Vardhman Mahavir Medical College, New Delhi, India
2 Institute of Pathology (ICMR), New Delhi - 110 029, India

Date of Web Publication5-May-2011

Correspondence Address:
Avninder Singh
Scientist-C, Institute of Pathology-ICMR, Safdarjung Hospital Campus, New Delhi - 110 029
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.80432

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How to cite this article:
Puri P, Singh A, Ramesh V. Facial nodule in a 34-year-old man. Indian J Dermatol 2011;56:230-1

How to cite this URL:
Puri P, Singh A, Ramesh V. Facial nodule in a 34-year-old man. Indian J Dermatol [serial online] 2011 [cited 2020 Nov 27];56:230-1. Available from: https://www.e-ijd.org/text.asp?2011/56/2/230/80432

A 34-year-old man presented with an asymptomatic nodular mass on his right cheek of two years' duration [Figure 1]. It initially appeared as a small papule that gradually increased to its present size. Physical examination revealed a firm, nontender bilobed tumor measuring 2.5 Χ 2 Χ 1 cm in size. There was no cervical lymphadenopathy. The tumor was mobile and distinct from surrounding structures. The differential diagnosis of dermatofibroma, pilomatricoma, and sebaceous cyst were considered. Surgically excised nodule was sent for histopathological examination. The patient was advised to come for follow-up.
Figure 1: A solitary bilobed nodule on the cheek

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Microscopic examination of the excised lesion showed a well-circumscribed tumor located in the deep dermis and seen extending into subcutaneous tissue [Figure 2]. A biphasic growth pattern could be readily appreciated and consisted of epithelial component embedded in a mixture of abundant fibrous and myxochondroid stroma [Figure 3]. The epithelial component consisted of branching and nonbranching tubules, cords, and dilated cystic structures with secretions in their lumina. The tubules demonstrated an eccrine differentiation, with lining of luminal layer with cuboidal cells and a peripheral layer of flattened cells. The peripheral layer of cells merged with the stroma that stained strongly with alcian blue.
Figure 2: well-circumscribed dermal nodule. (H and E, x 40)

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Figure 3: Biphasic tumor composed of myxochondroid stroma and epithelial component. (H and E, x 200)

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   Question Top

What is your diagnosis?

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   References Top

1.Kitsawa T, Hataya Y, Matsuo K. Chondroid syringoma of the orbit. Ann Plast Surg 1999;42:100-2.  Back to cited text no. 1
2.Hirsch P, Helwig EB. Chondroid syringoma-mixed tumour of skin, salivary gland type. Arch Dermatol 1961;84:835-47.  Back to cited text no. 2
3.Yavuzes R, Bastarzi Y, Sari A, Bir F, Sezer C. Chondroid syringoma: A diagnosis more frequent than expected. Dermatol Surg 2003;29:179-81.  Back to cited text no. 3
4.Mathiasen RA, Rusgon BM, Rumore G. Malignant chondroid syringoma of the face: A first reported case. Otolaryngol Head Neck Surg 2005;133: 305-7.  Back to cited text no. 4
5.Nather A, Sutherland IH. Malignant transformation of a benign cutaneous mixed tumour. J Hand Surg Br 1986;11:139-43.  Back to cited text no. 5
6.Kose R, Okur MI. Giant facial chondroid syringoma. Dermatol Surg 2009;35:294-5.  Back to cited text no. 6


  [Figure 1], [Figure 2], [Figure 3]


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