Indian Journal of Dermatology
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Year : 2008  |  Volume : 53  |  Issue : 4  |  Page : 201-203

Unusual presentation of generalized macular amyloidosis in a young adult

Department of Dermatology, Kasturba Medical College, Manipal, India

Correspondence Address:
Mohan H Kudur
Department of Dermatology, Kasturba Medical College, Manipal - 576 104
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5154.44802

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Macular amyloidosis is a common problem seen dermatology out-patient department. Generalized macular amyloidosis presenting with a poikilodermatous appearance is rare. In our case, an 18-year-old male presented with generalized hypopigmented macules with a poikilodermatous appearance of 10-year duration. His developmental milestones were normal with negative family history of similar complaints. Histopathology of hyperpigmented lesions revealed hyperkeratosis and acanthosis of epidermis and hypopigmented lesion showing only hyperkeratosis. Both lesions were showing the deposition of amorphous, hazy material in the tips of papillary dermis with perivascular inflammatory infiltrate. Congo red staining of the amorphous material was positive for amyloid.

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