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REVIEW ARTICLE
Year : 2008  |  Volume : 53  |  Issue : 4  |  Page : 163-166
Aloe vera: A short review

Amar Surjushe, Resham Vasani, DG Saple
Department of Dermatology, Venereology and Leprosy, Grant Medical College and Sir J J Group of Hospitals, Mumbai - 400 008 Maharashtra, India

Correspondence Address:
Amar Surjushe
Department of Dermatology, Venereology and Leprosy, Grant Medical College, Gokuldas Tejpal Hospital, Mumbai - 400 008, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.44785

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   Abstract 

Aloe vera is a natural product that is now a day frequently used in the field of cosmetology. Though there are various indications for its use, controlled trials are needed to determine its real efficacy. The aloe vera plant, its properties, mechanism of action and clinical uses are briefly reviewed in this article.


Keywords: Aloe vera, health and beauty, skin


How to cite this article:
Surjushe A, Vasani R, Saple D G. Aloe vera: A short review. Indian J Dermatol 2008;53:163-6

How to cite this URL:
Surjushe A, Vasani R, Saple D G. Aloe vera: A short review. Indian J Dermatol [serial online] 2008 [cited 2022 May 25];53:163-6. Available from: https://www.e-ijd.org/text.asp?2008/53/4/163/44785



   Introduction Top


The Aloe vera plant has been known and used for centuries for its health, beauty, medicinal and skin care properties. The name Aloe vera derives from the Arabic word "Alloeh" meaning "shining bitter substance," while "vera" in Latin means "true." 2000 years ago, the Greek scientists regarded Aloe vera as the universal panacea. The Egyptians called Aloe "the plant of immortality." Today, the Aloe vera plant has been used for various purposes in dermatology.

History

Aloe vera has been used for medicinal purposes in several cultures for millennia: Greece, Egypt, India, Mexico, Japan and China. [1] Egyptian queens Nefertiti and Cleopatra used it as part of their regular beauty regimes. Alexander the Great, and Christopher Columbus used it to treat soldiers' wounds. The first reference to Aloe vera in English was a translation by John Goodyew in A.D. 1655 of Dioscorides' Medical treatise De Materia Medica. [2] By the early 1800s, Aloe vera was in use as a laxative in the United States, but in the mid-1930s, a turning point occurred when it was successfully used to treat chronic and severe radiation dermatitis. [2]

Plant

The botanical name of Aloe vera is Aloe barbadensis miller . It belongs to Asphodelaceae (Liliaceae) family, and is a shrubby or arborescent, perennial, xerophytic, succulent, pea- green color plant. It grows mainly in the dry regions of Africa, Asia, Europe and America. In India, it is found in Rajasthan, Andhra Pradesh, Gujarat, Maharashtra and Tamil Nadu.

Anatomy

The plant has triangular, fleshy leaves with serrated edges, yellow tubular flowers and fruits that contain numerous seeds. Each leaf is composed of three layers: 1) An inner clear gel that contains 99% water and rest is made of glucomannans, amino acids, lipids, sterols and vitamins. 2) The middle layer of latex which is the bitter yellow sap and contains anthraquinones and glycosides. 3) The outer thick layer of 15-20 cells called as rind which has protective function and synthesizes carbohydrates and proteins. Inside the rind are vascular bundles responsible for transportation of substances such as water (xylem) and starch (phloem). [3]

 Active components with its properties: Aloe vera contains 75 potentially active constituents: vitamins, enzymes, minerals, sugars, lignin, saponins, salicylic acids and amino acids. [4],[5],[6]

  1. Vitamins : It contains vitamins A (beta-carotene), C and E, which are antioxidants. It also contains vitamin B12, folic acid, and choline. Antioxidant neutralizes free radicals.
  2. Enzymes : It contains 8 enzymes: aliiase, alkaline phosphatase, amylase, bradykinase, carboxypeptidase, catalase, cellulase, lipase, and peroxidase. Bradykinase helps to reduce excessive inflammation when applied to the skin topically, while others help in the breakdown of sugars and fats.
  3. Minerals: It provides calcium, chromium, copper, selenium, magnesium, manganese, potassium, sodium and zinc. They are essential for the proper functioning of various enzyme systems in different metabolic pathways and few are antioxidants.
  4. Sugars: It provides monosaccharides (glucose and fructose) and polysaccharides: (glucomannans/polymannose). These are derived from the mucilage layer of the plant and are known as mucopolysaccharides. The most prominent monosaccharide is mannose-6-phosphate, and the most common polysaccharides are called glucomannans [beta-(1,4)-acetylated mannan]. Acemannan, a prominent glucomannan has also been found. Recently, a glycoprotein with antiallergic properties, called alprogen and novel anti-inflammatory compound, C-glucosyl chromone, has been isolated from Aloe vera gel. [7],[8]
  5. Anthraquinones: It provides 12 anthraquinones, which are phenolic compounds traditionally known as laxatives. Aloin and emodin act as analgesics, antibacterials and antivirals.
  6. Fatty acids: It provides 4 plant steroids; cholesterol, campesterol, β-sisosterol and lupeol. All these have anti-inflammatory action and lupeol also possesses antiseptic and analgesic properties.
  7. Hormones: Auxins and gibberellins that help in wound healing and have anti-inflammatory action.
  8. Others : It provides 20 of the 22 human required amino acids and 7 of the 8 essential amino acids. It also contains salicylic acid that possesses anti-inflammatory and antibacterial properties. Lignin, an inert substance, when included in topical preparations, enhances penetrative effect of the other ingredients into the skin. Saponins that are the soapy substances form about 3% of the gel and have cleansing and antiseptic properties.


Mechanism of actions

  1. Healing properties: Glucomannan, a mannose-rich polysaccharide, and gibberellin, a growth hormone, interacts with growth factor receptors on the fibroblast, thereby stimulating its activity and proliferation, which in turn significantly increases collagen synthesis after topical and oral Aloe vera. [9] Aloe gel not only increased collagen content of the wound but also changed collagen composition (more type III) and increased the degree of collagen cross linking. Due to this, it accelerated wound contraction and increased the breaking strength of resulting scar tissue. [10] An increased synthesis of hyaluronic acid and dermatan sulfate in the granulation tissue of a healing wound following oral or topical treatment has been reported. [11]
  2. Effects on skin exposure to UV and gamma radiation: Aloe vera gel has been reported to have a protective effect against radiation damage to the skin. [12],[13] Exact role is not known, but following the administration of aloe vera gel, an antioxidant protein, metallothionein, is generated in the skin, which scavenges hydroxyl radicals and prevents suppression of superoxide dismutase and glutathione peroxidase in the skin. It reduces the production and release of skin keratinocyte-derived immunosuppressive cytokines such as interleukin-10 (IL-10) and hence prevents UV-induced suppression of delayed type hypersensitivity. [14]
  3. Anti-inflammatory action: Aloe vera inhibits the cyclooxygenase pathway and reduces prostaglandin E2 production from arachidonic acid. Recently, the novel anti-inflammatory compound called C-glucosyl chromone was isolated from gel extracts. [8]
  4. Effects on the immune system: Alprogen inhibit calcium influx into mast cells, thereby inhibiting the antigen-antibody-mediated release of histamine and leukotriene from mast cells. [7] In a study on mice that had previously been implanted with murine sarcoma cells, acemannan stimulates the synthesis and release of interleukin-1 (IL-1) and tumor necrosis factor from macrophages in mice, which in turn initiated an immune attack that resulted in necrosis and regression of the cancerous cells. [15] Several low-molecular-weight compounds are also capable of inhibiting the release of reactive oxygen free radicals from activated human neutrophils. [16]
  5. Laxative effects: Anthraquinones present in latex are a potent laxative. It increases intestinal water content, stimulates mucus secretion and increases intestinal peristalsis. [17]
  6. Antiviral and antitumor activity: These actions may be due to indirect or direct effects. Indirect effect is due to stimulation of the immune system and direct effect is due to anthraquinones. The anthraquinone aloin inactivates various enveloped viruses such as herpes simplex, varicella zoster and influenza. [18] In recent studies, a polysaccharide fraction has shown to inhibit the binding of benzopyrene to primary rat hepatocytes, thereby preventing the formation of potentially cancer-initiating benzopyrene-DNA adducts. An induction of glutathione S-transferase and an inhibition of the tumor-promoting effects of phorbol myristic acetate has also been reported which suggest a possible benefit of using aloe gel in cancer chemoprevention. [19],[20]
  7. Moisturizing and anti-aging effect: Mucopolysaccharides help in binding moisture into the skin. Aloe stimulates fibroblast which produces the collagen and elastin fibers making the skin more elastic and less wrinkled. It also has cohesive effects on the superficial flaking epidermal cells by sticking them together, which softens the skin. The amino acids also soften hardened skin cells and zinc acts as an astringent to tighten pores. Its moisturizing effects has also been studied in treatment of dry skin associated with occupational exposure where aloe vera gel gloves improved the skin integrity, decreases appearance of fine wrinkle and decreases erythema. [21] It also has anti-acne effect.
  8. Antiseptic effect: Aloe vera contains 6 antiseptic agents: Lupeol, salicylic acid, urea nitrogen, cinnamonic acid, phenols and sulfur. They all have inhibitory action on fungi, bacteria and viruses.


Clinical uses: The clinical use of aloe vera is supported mostly by anecdotal data. Though most of these uses are interesting, controlled trials are essential to determine its effectiveness in all the following diseases. [22],[23]

 A. Uses based on scientific evidence: These uses have been tested in humans or animals. Safety and effectiveness have not always been proven.

Conditions: Seborrheic dermatitis, [24] psoriasis vulgaris, [25],[26] genital herpes, [27],[28] skin burns, [5],[29] diabetes (type 2), [30] HIV infection, [31] cancer prevention, [32],[33] ulcerative colitis [34] wound healing (results of aloe on wound healing are mixed with some studies reporting positive results [35] and others showing no benefit [36] or potential worsening [37],[38] ), pressure ulcers, [36] mucositis, [39] radiation dermatitis, [40] acne vulgaris, [41] lichen planus, [42] frostbite, [43] aphthous stomatitis, [44] and constipation. [17]

B. Uses based on tradition or theory: The below uses are based on tradition or scientific theories. They often have not been thoroughly tested in humans, and safety and effectiveness have not always been proven.

Conditions: Alopecia, bacterial and fungal skin infections, chronic leg wounds, parasitic infections, systemic lupus erythematosus, arthritis and tic douloureux.

Side effects

Topical: It may cause redness, burning, stinging sensation and rarely generalized dermatitis in sensitive individuals. Allergic reactions are mostly due to anthraquinones, such as aloin and barbaloin. It is best to apply it to a small area first to test for possible allergic reaction.

Oral: Abdominal cramps, diarrhea, red urine, hepatitis, dependency or worsening of constipation. Prolonged use has been reported to increase the risk of colorectal cancer. Laxative effect may cause electrolyte imbalances (low potassium levels).

Contraindication: Contraindicated in cases of known allergy to plants in the Liliaceae family.

Pregnancy and breastfeeding: Oral aloe is not recommended during pregnancy due to theoretical stimulation of uterine contractions, and in breastfeeding mothers, it may sometime causes gastrointestinal distress in the nursing infant.

Interactions : Application of aloe to skin may increase the absorption of steroid creams such as hydrocortisone. It reduces the effectiveness and may increases the adverse effects of digoxin and digitoxin, due to its potassium lowering effect. Combined use of Aloe vera and furosemide may increase the risk of potassium depletion. It decreases the blood sugar levels and thus may interact with oral hypoglycemic drugs and insulin.

Thus, though Aloe vera has wide spectrum of the properties and uses, some of them could be myths and some of them could be real magic. In future, controlled studies are required to prove the effectiveness of Aloe vera under various conditions.

 
   References Top

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39.Su K, Mehta V, Ravikumar L, Shah R, Pinto H, Halpern J, et al. Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms. Int J Radiat Oncol Biol Phys 2004;60:71-7.  Back to cited text no. 39    
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[Pubmed] | [DOI]
24 Clinical interventions for tungiasis (sand flea disease): a systematic review
Solomon Abrha, Jorg Heukelbach, Gregory M Peterson, Julia K Christenson, Simon Carroll, Sam Kosari, Andrew Bartholomeus, Hermann Feldmeier, Jackson Thomas
The Lancet Infectious Diseases. 2021; 21(8): e234
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25 Delivery of Therapeutics from Layer-by-Layer Electrospun Nanofiber Matrix for Wound Healing: An Update
Tracey Anastacia Jeckson, Yun Ping Neo, Sreenivas Patro Sisinthy, Bapi Gorain
Journal of Pharmaceutical Sciences. 2021; 110(2): 635
[Pubmed] | [DOI]
26 Polyvinyl alcohol (PVA) mixed green–clay and aloe vera based polymeric membrane optimization: Peel-off mask formulation for skin care cosmeceuticals in green nanotechnology
Nidhi Asthana, Kaushik Pal, Alaa A.A. Aljabali, Murtaza M. Tambuwala, Fernando Gomes de Souza, Kamlesh Pandey
Journal of Molecular Structure. 2021; 1229: 129592
[Pubmed] | [DOI]
27 Advanced SA/PVA-based hydrogel matrices with prolonged release of Aloe vera as promising wound dressings
Katarzyna Bialik-Was, Klaudia Pluta, Dagmara Malina, Mateusz Barczewski, Katarzyna Malarz, Anna Mrozek-Wilczkiewicz
Materials Science and Engineering: C. 2021; 120: 111667
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28 Perspective on the application of medicinal plants and natural products in wound healing: A mechanistic review
Omid Yazarlu, Mehrdad Iranshahi, Hamid Reza Khayat Kashani, Sara Reshadat, Solomon Habtemariam, Milad Iranshahy, Maede Hasanpour
Pharmacological Research. 2021; 174: 105841
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29 Aloe vera gel: An update on its use as a functional edible coating to preserve fruits and vegetables
Iolanda Nicolau-Lapeña, Pilar Colàs-Medà, Isabel Alegre, Ingrid Aguiló-Aguayo, Peter Muranyi, Inmaculada Viñas
Progress in Organic Coatings. 2021; 151: 106007
[Pubmed] | [DOI]
30 Elucidation of genetic diversity and population structure of sixty genotypes of Aloe vera using AFLP markers
Ravinder Kumar, Raj Kumar Salar, Pradeep K Naik, Manju Yadav, Anil Kumar, Ashok Kumar, Rajesh Yogi, Mukesh Kumar, Vinod Chhokar
South African Journal of Botany. 2021;
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31 Reverse pharmacology of phytoconstituents of food and plant in the management of diabetes: Current status and perspectives
Kalvatala Sudhakar, Vijay Mishra, Varshik Hemani, Arpit Verma, Ankush Jain, Sanjay Jain, R. Narayana Charyulu
Trends in Food Science & Technology. 2021; 110: 594
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32 Cosmetologia della pelle nera
F. Ly
EMC - Cosmetologia Medica e Medicina degli Inestetismi Cutanei. 2021; 18(1): 1
[Pubmed] | [DOI]
33 Aloe Vera Flower Extract as a Botanical Resistive Memory Element: A Natural Memristor!
Tanushree Ghosh, Suchita Kandpal, Devesh K. Pathak, Manushree Tanwar, Chanchal Rani, Anjali Chaudhary, Rajesh Kumar
ACS Applied Electronic Materials. 2021; 3(4): 1556
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34 Biocompatible CuInS2 Nanoparticles as Potential Antimicrobial, Antioxidant, and Cytotoxic Agents
Ranjan Kr. Giri, Sunil Chaki, Ankurkumar J. Khimani, Yati H. Vaidya, Parth Thakor, Anjali B. Thakkar, Swati J. Pandya, Milind P. Deshpande
ACS Omega. 2021; 6(40): 26533
[Pubmed] | [DOI]
35 Phosphorous Use Efficiency and Its Requirement for Aloe Vera Cultivated on Silty Loam Soils
Taslima Sultana, Akhter Hossain Chowdhury, Arifur Rahman, Biplob Kumar Saha, Tanzin Chowdhury, Mohammed Ariful Islam, Rubeca Fancy
Communications in Soil Science and Plant Analysis. 2021; 52(3): 268
[Pubmed] | [DOI]
36 Integrated hydrothermal assisted green synthesis of ZnO nano discs and their water purification efficiency
Ambreen Ashar, Ijaz A. Bhatti, Tayyaba Siddique, Sobhy M. Ibrahim, Saima Mirza, Zeeshan A. Bhutta, Muhammad Shoaib, Moazam Ali, Muhammad B. Taj, Munawar Iqbal, Sadia Noor, Muhammad Mohsin
Journal of Materials Research and Technology. 2021;
[Pubmed] | [DOI]
37 Role of zonulin and GLP-1/DPP-IV in alleviation of diabetes mellitus by peptide/polypeptide fraction of Aloe vera in streptozotocin- induced diabetic wistar rats
Spoorthy N. Babu, S. Govindarajan, M.A. Vijayalakshmi, Ayesha Noor
Journal of Ethnopharmacology. 2021; 272: 113949
[Pubmed] | [DOI]
38 Molecular docking and ADMET studies to predict the anti-breast cancer effect of aloin by targeting estrogen and progesterone receptors
Shalini Mani, Geeta Swargiary, Sasha Gulati, Simmi Gupta, Divya Jindal
Materials Today: Proceedings. 2021;
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39 Vitamin E boosted the protective potential of Aloe vera in CCl4-treated rats
Rida Fatima, Muhammaed Shiraz Yasin, Hira Anwar, Ihsan Ullah, Wasim Shehzad, Iram Murtaza, Tahir Ali
Biologia. 2021;
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40 Optimized irrigation regime and planting technique improve yields and economics in aloe vera [Aloe barbadensis (Miller)]
Anjali Singh, Kirti Verma, Devendra Kumar, Nilofer, Nikil Bhashkar Lothe, Anuj Kumar, Archana Chaudhary, Parminder Kaur, Kushal Pal Singh, Anil Kumar Singh, Rakesh Kumar, Anandakumar T.M, Saudan Singh
Industrial Crops and Products. 2021; 167: 113539
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41 Advances in Soft Materials for Sustainable Electronics
Moon Jong Han, Dong Ki Yoon
Engineering. 2021; 7(5): 564
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42 Plant-based mucilage with healing and anti-inflammatory actions for topical application: A review
Josemar Gonçalves de Oliveira Filho, Michelle Monteiro Lira, Tainara Leal de Sousa, Stéphani Borges Campos, Ailton Cesar Lemes, Mariana Buranelo Egea
Food Hydrocolloids for Health. 2021; 1: 100012
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43 Effects of Aloe vera utilization on physochemical and microbiological properties of Turkish dry fermented sausage
Eyüp Usan, Gülden Basyigit Kiliç, Birol Kiliç
Journal of Food Science and Technology. 2021;
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44 NiO bio-composite materials: Photocatalytic, electrochemical and supercapacitor applications
B. Avinash, C.R. Ravikumar, M.R. Anil Kumar, M.S. Santosh, C. Pratapkumar, H.P. Nagaswarupa, H.C. Ananda Murthy, V.V. Deshmukh, Aarti S. Bhatt, A.A. Jahagirdar, Mir Waqas Alam
Applied Surface Science Advances. 2021; 3: 100049
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45 Interventions non médicamenteuses et cancer du sein : quel bénéfice en complément d’une radiothérapie ?
Béatrice Lognos, Murielle Glondu-Lassis, Pierre Senesse, Marian Gutowski, William Jacot, Claire Lemanski, Michel Amouyal, David Azria, Estelle Guerdoux, Céline Bourgier
Cancer/Radiothérapie. 2021;
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46 Functional Applications of Aloe vera on Textiles: A Review
Md. Ibrahim H. Mondal, Joykrisna Saha, Md. Ashadur Rahman
Journal of Polymers and the Environment. 2021; 29(4): 993
[Pubmed] | [DOI]
47 Green synthesis of amorphous calcium phosphate nanopowders using Aloe Vera plant extract and assessment of their cytotoxicity and antimicrobial activities
Sima Beigoli, Azadeh Hekmat, Fahimeh Farzanegan, Majid Darroudi
Journal of Sol-Gel Science and Technology. 2021; 98(3): 508
[Pubmed] | [DOI]
48 Quantitative determination of aloin, antioxidant activity, and toxicity of Aloe vera leaf gel products from Greece
Eleftheria H Kaparakou, Charalabos D Kanakis, Maria Gerogianni, Matina Maniati, Kostas Vekrellis, Efstathia Skotti, Petros A Tarantilis
Journal of the Science of Food and Agriculture. 2021; 101(2): 414
[Pubmed] | [DOI]
49 Aloe vera and health outcomes: An umbrella review of systematic reviews and meta-analyses
Saranrat Sadoyu, Chidchanok Rungruang, Thitima Wattanavijitkul, Ratree Sawangjit, Ammarin Thakkinstian, Nathorn Chaiyakunapruk
Phytotherapy Research. 2021; 35(2): 555
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50 Pharmacodynamics of Aloe vera and acemannan in therapeutic applications for skin, digestion, and immunomodulation
Nicholas J. Sadgrove, Monique S. J. Simmonds
Phytotherapy Research. 2021;
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51 3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery
Rafaela Santos de Oliveira, Stephani Silva Fantaus, Antonio José Guillot, Ana Melero, Ruy Carlos Ruver Beck
Pharmaceutics. 2021; 13(11): 1946
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52 Antimicrobial Efficiency of Aloe arborescens and Aloe barbadensis Natural and Commercial Products
Kaja Kupnik, Mateja Primožic, Željko Knez, Maja Leitgeb
Plants. 2021; 10(1): 92
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53 Biotechnological Applications of Polymeric Nanofiber Platforms Loaded with Diverse Bioactive Materials
M. R. El-Aassar, Omar M. Ibrahim, Ziad H. Al-Oanzi
Polymers. 2021; 13(21): 3734
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54 Adipocyte differentiation inhibition, whitening, antibacterial and antioxidant activities of extracts from Aloe vera by-product
Seong-Hun Lee, Chang-Ho Eun, Jin-Hong Baek, In-Jung Kim
Journal of Applied Biological Chemistry. 2021; 64(2): 171
[Pubmed] | [DOI]
55 Aloe Vera-Mediated Te Nanostructures: Highly Potent Antibacterial Agents and Moderated Anticancer Effects
David Medina-Cruz, Ada Vernet-Crua, Ebrahim Mostafavi, María Ujué González, Lidia Martínez, A-Andrew D. Jones III, Matthew Kusper, Eduardo Sotelo, Ming Gao, Luke D. Geoffrion, Veer Shah, Grégory Guisbiers, Jorge L. Cholula-Díaz, Christelle Guillermier, Fouzia Khanom, Yves Huttel, José Miguel García-Martín, Thomas J. Webster
Nanomaterials. 2021; 11(2): 514
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56 Enzymatic and Antimicrobial Activity of Biologically Active Samples from Aloe arborescens and Aloe barbadensis
Maja Leitgeb, Kaja Kupnik, Željko Knez, Mateja Primožic
Biology. 2021; 10(8): 765
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57 Flavonoids and Omega3 Prevent Muscle and Cardiac Damage in Duchenne Muscular Dystrophy Animal Model
Luana Tripodi, Davide Molinaro, Andrea Farini, Gendenver Cadiao, Chiara Villa, Yvan Torrente
Cells. 2021; 10(11): 2917
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58 Immunobiology and Application of Aloe vera-Based Scaffolds in Tissue Engineering
Saeedeh Darzi, Kallyanashis Paul, Shanilka Leitan, Jerome A. Werkmeister, Shayanti Mukherjee
International Journal of Molecular Sciences. 2021; 22(4): 1708
[Pubmed] | [DOI]
59 Nutritional, Textural, and Sensory Quality of Aloe Vera Leaf Gel Powder Fortified Plain Cake
Dhrubajyoti Singha, Md. Fahad Jubayer, Kumkum Devnath, Delara Akhter, Thottiam Vasudevan Ranganathan, Md. Towhidur Rahman, Md. Anisur Rahman Mazumder
J. 2021; 4(3): 430
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60 Efficacy of Aloe vera Gel on the Excision Wound Healing in Sprague dawley Rats
Bagus Uda Palgunadi, Asih Rahayu, Yos Adi Prakoso
Medicra (Journal of Medical Laboratory Science/Technology). 2021; 4(1): 46
[Pubmed] | [DOI]
61 Immunomodulatory Effects of Medicinal Plants used for Vitiligo in Traditional Persian Medicine
Mohsen Haghir Ebrahimabadi, Seyede Nargess Sadati Lamardi, Laila Shirbeigi
Current Drug Discovery Technologies. 2021; 18(2): 160
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62 Herbal Medicines for Diabetes Management and its Secondary Complications
Shubham Kumar, Anu Mittal, Dinesh Babu, Amit Mittal
Current Diabetes Reviews. 2021; 17(4): 437
[Pubmed] | [DOI]
63 Aloe Vera (Aloe barbadensis) Gel for the Management of Gastroesophageal Reflux Disease (GERD)
Mohaddese Mahboubi
The Natural Products Journal. 2021; 11(1): 13
[Pubmed] | [DOI]
64 Green Silver Nanoparticles Embedded in Cellulosic Network for Fresh Food Packaging
S. Chaitanya Kumari, P. Naga Padma, K. Anuradha
Journal of Pure and Applied Microbiology. 2021; 15(3): 1236
[Pubmed] | [DOI]
65 Sibr (Aloe barbadensis): A Short Description with Unani Approach
Hilal Akhtar, Mohammad Wasi Akhtar, Mohammad Saad Ahmad Khan, Syed Zeba Husain
Journal of Drug Delivery and Therapeutics. 2021; 11(2): 224
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66 Scope of herbal mucilage in pharmaceutical formulations. A review
Fels Saju, Chinju M Sivaraman
Herba Polonica. 2021; 67(1): 46
[Pubmed] | [DOI]
67 Aloe Vera Jel Içecegi Ile Zenginlestilmis Probiyotik Yogurt Üretimi
Cansu SÖKÜT, Gülden BASYIGIT KILIÇ, Sultan BARIN, Asli ALBAYRAK
Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü Dergisi. 2021;
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68 Response of Aloe vera to potassium fertilization in relation to leaf biomass yield, its uptake and requirement, critical concentration and use efficiency
Taslima Sultana, Akhter Hossain Chowdhury, Biplob Kumar Saha, Arifur Rahman, Tanzin Chowdhury, Razia Sultana
Journal of Plant Nutrition. 2021; 44(14): 2081
[Pubmed] | [DOI]
69 Bactericidal and fungicidal capacity of Ag2O/Ag nanoparticles synthesized with Aloe vera extract
N. S. Flores-Lopez, J. A. Cervantes-Chávez, D. G. Téllez de Jesús, M. Cortez-Valadez, M. Estévez-González, R. Esparza
Journal of Environmental Science and Health, Part A. 2021; 56(7): 762
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70 Evaluation of clinical trials for natural products used in diabetes
Rizwan Ahmad, Lina Hussain AlLehaibi, Hind Nasser AlSuwaidan, Ali Fuad Alghiryafi, Lyla Shafiq Almubarak, Khawlah Nezar AlKhalifah, Hawra Jassim AlMubarak, Majed Ali Alkhathami
Medicine. 2021; 100(16): e25641
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71 Effects of Aloe vera in adults with mucocutaneous problems: A systematic review and meta-analysis
Zehra Gok Metin, Aylin Helvaci, Merve Gulbahar Eren
Journal of Advanced Nursing. 2021; 77(3): 1105
[Pubmed] | [DOI]
72 A comparison of the efficacy of silicone gel containing onion extract and aloe vera to silicone gel sheets to prevent postoperative hypertrophic scars and keloids
Watsachon Pangkanon, Putthiporn Yenbutra, Nanticha Kamanamool, Apichaya Tannirandorn, Montree Udompataikul
Journal of Cosmetic Dermatology. 2021; 20(4): 1146
[Pubmed] | [DOI]
73 Designing an ideal alcohol-based hand sanitizer: in vitro antibacterial responses of ethanol and isopropyl alcohol solutions to changing composition
Ifeanyi T. Nzekwe, Onyedika I. Agwuka, Moses U. Okezie, Daniel O. Fasheun, Petra O. Nnamani, Chukwuma O. Agubata
AAPS Open. 2021; 7(1)
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74 Aloe vera gel homogenate shows anti-inflammatory activity through lysosomal membrane stabilization and downregulation of TNF-a and Cox-2 gene expressions in inflammatory arthritic animals
Subhashis Paul, Debabrata Modak, Sutanuka Chattaraj, Deblina Nandi, Aditi Sarkar, Joyjit Roy, Tapas Kumar Chaudhuri, Soumen Bhattacharjee
Future Journal of Pharmaceutical Sciences. 2021; 7(1)
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75 Review on the phytochemistry and toxicological profiles of Aloe vera and Aloe ferox
Florence Nalimu, Joseph Oloro, Ivan Kahwa, Patrick Engeu Ogwang
Future Journal of Pharmaceutical Sciences. 2021; 7(1)
[Pubmed] | [DOI]
76 Anti-Inflammatory, Antioxidant, and Healing-Promoting Effects of Aloe vera Extract in the Experimental Colitis in Rats
Mahvash Alizade Naini, Asal Zargari-Samadnejad, Shayan Mehrvarz, Romina Tanideh, Mohammad Ghorbani, Amirreza Dehghanian, Maryam Hasanzarrini, Farnaz Banaee, Omid Koohi-Hosseinabadi, Nader Tanideh, Aida Iraji, Kuo-Tong Liou
Evidence-Based Complementary and Alternative Medicine. 2021; 2021: 1
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77 Optimization of the green synthesis of silver nanoparticle with Box-Behnken design: Using Aloe vera plant extract as a reduction agent
Nazan GÖKSEN, Özlem KAPLAN
Sakarya University Journal of Science. 2021;
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78 A comparative clinical evaluation of the effect of chamomile, Aloe Vera and chlorhexidine 0.12% mouthwash on gingival health among visually impaired
Mari Nema
International Journal of Oral Health Dentistry. 2021; 6(4): 273
[Pubmed] | [DOI]
79 Novel Composition of Multifunctional Sunblock from Eisenia bicyclis and Aloe vera Extracts and a Mixed Compound of Titanium Dioxide
Dong-Myong Kim, Ju-Yeong Jung, Hyung-Kon Lee, Sang-Keun Park, Yong-Seong Kwon, Seung-Koo Yang, In-Suk Han
Asian Journal of Beauty and Cosmetology. 2020; 18(3): 297
[Pubmed] | [DOI]
80 Phasing out contentious inputs in organic and non-organic horticulture – Organic-PLUS
U. Schmutz, F. Rayns, N. Katsoulas, A.K. Løes, M. De Marchi, C.G. Sørensen, A. Evans
Acta Horticulturae. 2020; (1286): 211
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81 In Vitro Micropropagation of Industrially and Medicinally Useful Plant Aloe trichosantha Berger Using Offshoot Cuttings
Atsbeha Hailu, Desta Berhe Sbhatu, Haftom Baraki Abraha
The Scientific World Journal. 2020; 2020: 1
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82 Home remedies in different pediatric dermatoses: An observational study
Mrinal Gupta, Shashank Bhargava
Dermatologic Therapy. 2020; 33(6)
[Pubmed] | [DOI]
83 Efficacy of a Natural Topical Skin Ointment for Managing Split-Thickness Skin Graft Donor Sites: A Pilot Double-blind Randomized Controlled Trial
Mohammad Saeed Abbasi, Javad Rahmati, Amir Houshang Ehsani, Alireza Takzare, Alireza Partoazar, Nasrin Takzaree
Advances in Skin & Wound Care. 2020; 33(7): 1
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84 Hypoglycaemic, insulin releasing, and hepatoprotective effect of the aqueous extract of Aloe perryi Baker resin (Socotran Aloe) in streptozotocin-induced diabetic rats
Tahany Saleh Aldayel, Ghedeir M. Alshammari, Ulfat Mohammed Omar, Mary H. Grace, Mary Ann Lila, Mohammed A. Yahya
Journal of Taibah University for Science. 2020; 14(1): 1671
[Pubmed] | [DOI]
85 Wound healing activity of skin incision and skin burn from spray gel formula contains combination of banana stem (Musa acuminata Colla) and Aloe vera ethanol extracts on mice
W Kundarto, K A Y Pangesti, F Shabrina, H Sasongko
IOP Conference Series: Materials Science and Engineering. 2020; 858(1): 012027
[Pubmed] | [DOI]
86 Protective effect of Aloe vera on growth performance, leucocyte count and intestinal injury in broiler chicken infected with coccidiosis
Zahoor Ahmad, Abdul Hafeez, Qudrat Ullah, Shabana Naz, Rifat Ullah Khan
Journal of Applied Animal Research. 2020; 48(1): 252
[Pubmed] | [DOI]
87 Herbal Medications for the Management of Diabetes Mellitus: A Review
Bilal A. Al-Jaidi, Haifa'a Marouf Odetallah, Balakumar Chandrasekaran, Razan Amro
Current Traditional Medicine. 2020; 6(4): 332
[Pubmed] | [DOI]
88 ALOE VERA’NIN GIDA ENDÜSTRISINDE KULLANIMI
Gülden BASYIGIT KILIÇ, Damla BILECEN SEN, Dania ALNAKDALI, Müberra GÜLSEN
Mühendislik Bilimleri ve Tasarim Dergisi. 2020; 8(1): 326
[Pubmed] | [DOI]
89 Comparison of Ag, Cu and Zn nanoparticles obtained using Aloe vera extract and gamma ionizing radiation
C. Martínez Vieyra, M.T Olguin, E. Gutiérrez Segura, G. López Tellez
Journal of Applied Research and Technology. 2020; 18(5)
[Pubmed] | [DOI]
90 Herbal Detoxifiers: An Eminent Need of Today
Rashmi S. Pal, Yogendra Pal, Ankita Wal, Pranay Wal
Current Nutrition & Food Science. 2020; 16(4): 424
[Pubmed] | [DOI]
91 Safety and Efficacy of Proctosoll Allevia in the Management of Haemorrhoidal Disease in Adults: A Prospective Randomized Clinical Trial
Alessandro Sturiale, Gaetano Gallo, Luigi Brusciano, Concetta Cacace, Danilo Cafaro, Felipe Celedon Porzio, Gabriele Naldini
Reviews on Recent Clinical Trials. 2020; 15(2): 152
[Pubmed] | [DOI]
92 A Review on Impact of Medicinal Plants on the Treatment of Oral and Dental Diseases
Balakrishnan Arumugam, Arunambiga Subramaniam , Praveena Alagaraj
Cardiovascular & Hematological Agents in Medicinal Chemistry. 2020; 18(2): 79
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93

Effects of Skin Lightening Cream Agents – Hydroquinone and Kojic Acid, on the Skin of Adult Female Experimental Rats
Joshua Oladele Owolabi, Oluseyi Sunday Fabiyi, Lola Adeola Adelakin, Miriammillicent Chinenyenwa Ekwerike
Clinical, Cosmetic and Investigational Dermatology. 2020; Volume 13: 283
[Pubmed] | [DOI]
94

Effect of Aloe vera Gel, Calendula officinalis Ointment and Simple Prophylactic Sacral Dressings for Pressure Injury Development
Mahmood Baghdadi, Hossein Rafiei, Farnoosh Rashvand, Sonia Oveisi
Chronic Wound Care Management and Research. 2020; Volume 7: 19
[Pubmed] | [DOI]
95

Lanthanides-Substituted Hydroxyapatite/Aloe vera Composite Coated Titanium Plate for Bone Tissue Regeneration
Selvakani Prabakaran, Mariappan Rajan, Changwei Lv, Guolin Meng
International Journal of Nanomedicine. 2020; Volume 15: 8261
[Pubmed] | [DOI]
96 Pharmacological Update Properties of Aloe Vera and its Major Active Constituents
Marta Sánchez, Elena González-Burgos, Irene Iglesias, M. Pilar Gómez-Serranillos
Molecules. 2020; 25(6): 1324
[Pubmed] | [DOI]
97 Transdermal Delivery Systems of Natural Products Applied to Skin Therapy and Care
Ying-Chen Cheng, Tzong Shiun Li, Hong Lin Su, Po Chun Lee, Hui-Min David Wang
Molecules. 2020; 25(21): 5051
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98 The Effect of Botanical Extracts Obtained through Ultrasound-Assisted Extraction on White Head Cabbage (Brassica Oleracea L. Var. Capitata L.) Seedlings Grown under Controlled Conditions
Katarzyna Godlewska, Anita Biesiada, Izabela Michalak, Pawel Pacyga
Sustainability. 2020; 12(5): 1871
[Pubmed] | [DOI]
99 Polyacrylamide-Metilcellulose Hydrogels Containing Aloe barbadensis Extract as Dressing for Treatment of Chronic Cutaneous Skin Lesions
Desireé Alesa Gyles, Anivaldo Duarte Pereira Júnior, Lorena Diniz Castro, Andressa Santa Brigida, Maria Louze Nobre Lamarão, Wagner Luiz Ramos Barbosa, José Otávio Carréra Silva Júnior, Roseane Maria Ribeiro-Costa
Polymers. 2020; 12(3): 690
[Pubmed] | [DOI]
100 Towards advanced wound regeneration
Ernest Man, Clare Hoskins
European Journal of Pharmaceutical Sciences. 2020; 149: 105360
[Pubmed] | [DOI]
101 Production of UF-soft cheese using probiotic bacteria and Aloe vera pulp as a good source of nutrients
Samah M. El-Sayed, Hoda S. El-Sayed
Annals of Agricultural Sciences. 2020; 65(1): 13
[Pubmed] | [DOI]
102 Nitrogen use efficiency and critical leaf N concentration of Aloe vera in urea and diammonium phosphate amended soil
Md. Akhter Hossain Chowdhury, Taslima Sultana, Md. Arifur Rahman, Tanzin Chowdhury, Christian Ebere Enyoh, Biplob Kumar Saha, Wang Qingyue
Heliyon. 2020; 6(12): e05718
[Pubmed] | [DOI]
103 Sulphur fertilization enhanced yield, its uptake, use efficiency and economic returns of Aloe vera L.
Md. Akhter Hossain Chowdhury, Taslima Sultana, Md. Arifur Rahman, Biplob Kumar Saha, Tanzin Chowdhury, Subrata Tarafder
Heliyon. 2020; 6(12): e05726
[Pubmed] | [DOI]
104 Post-transcriptional regulation activity through alternative splicing involved in the effects of Aloe vera on the Wnt/ß-catenin and Notch pathways in colorectal cancer cells
Chang Peng, WeiJia Zhang, Xue Shen, YueMei Yuan, Yan Li, Wei Zhang, MeiCun Yao
Journal of Pharmacological Sciences. 2020; 143(3): 148
[Pubmed] | [DOI]
105 Nutritional significance of aloe vera (Aloe barbadensis Miller) and its beneficial impact on poultry
Amany A. Ebrahim, Shaaban S. Elnesr, M. A. A. Abdel-Mageed, M. M. M. Aly
World's Poultry Science Journal. 2020; 76(4): 803
[Pubmed] | [DOI]
106 Exploring and applying the substrate promiscuity of a C-glycosyltransferase in the chemo-enzymatic synthesis of bioactive C-glycosides
Kebo Xie, Xiaolin Zhang, Songyang Sui, Fei Ye, Jungui Dai
Nature Communications. 2020; 11(1)
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107 Diabetic Wound Care: A Concise Review of Diabetic Wound and Skincare Ingredients
Mohammad Afsahi, Hamid Reza Ahmadi Ashtiani, Amir Hosein Askari Pour, Ebrahim Hazrati
Journal of Archives in Military Medicine. 2020; 8(2)
[Pubmed] | [DOI]
108 Clinical and Radiographic Evaluation of Aloe vera vs Formocresol as a Pulpotomy Medicament in Primary Molars: A Double Blinded Randomized Controlled Trial
Sujatha Somasundaram, Divya Subramanyam
International Journal of Clinical Pediatric Dentistry. 2020; 13(2): 138
[Pubmed] | [DOI]
109 Anti-inflammatory and anti-oxidant effects of aloe vera in rats with non-alcoholic steatohepatitis
Naruemon Klaikeaw, Jutamas Wongphoom, Duangporn Werawatganon, Maneerat Chayanupatkul, Prasong Siriviriyakul
World Journal of Hepatology. 2020; 12(7): 363
[Pubmed] | [DOI]
110 Anti-inflammatory and anti-oxidant effects of aloe vera in rats with non-alcoholic steatohepatitis
Naruemon Klaikeaw, Jutamas Wongphoom, Duangporn Werawatganon, Maneerat Chayanupatkul, Prasong Siriviriyakul
World Journal of Hepatology. 2020; 12(7): 364
[Pubmed] | [DOI]
111 Comprehensive review of hepatotoxicity associated with traditional Indian Ayurvedic herbs
Cyriac Abby Philips, Rizwan Ahamed, Sasidharan Rajesh, Tom George, Meera Mohanan, Philip Augustine
World Journal of Hepatology. 2020; 12(9): 574
[Pubmed] | [DOI]
112 ROLE OF RAJAHPRAVARTINI VATI IN THE MANAGEMENT OF PRIMARY DYSMENORRHOEA (KASHTARTAVA) – A CLINICAL STUDY
Namrata Patel, Sanjay Srivastava, Bharti Dadlani, Basanti Guru
International Ayurvedic Medical Journal. 2020; 8(10): 4633
[Pubmed] | [DOI]
113 Aloe Vera: A Miracle Plant with its Wide-Ranging Applications
Zeliha Selamoglu
Pharmacy & Pharmacology International Journal. 2018; 6(1)
[Pubmed] | [DOI]
114 Identification of phenolic constituents and antioxidant activity of Aloe barbadensis flower extracts
Trishna Debnath, Mithun Ghosh, Young Min Lee, Narayan Chandra Deb Nath, Kwang-Geun Lee, Beong Ou Lim
Food and Agricultural Immunology. 2018; 29(1): 27
[Pubmed] | [DOI]
115 Aloe vera gel: Effective Therapeutic agent against Extended-Spectrum ß-lactamase Producing Escherichia coli Isolated from Patients with Urinary Tract Infection in Tehran-Iran
Mehdi Goudarzi, Saeedeh Ghafari, Masoumeh Navidinia, Hadi Azimi
Journal of Pure and Applied Microbiology. 2017; 11(3): 1401
[Pubmed] | [DOI]
116 Effect of Coating of Aloe Vera Gelon Shelf Life of Grapes
Javed Ali, Suyash Pandey, Vaishali Singh, Prerna Joshi
Current Research in Nutrition and Food Science Journal. 2016; 4(1): 58
[Pubmed] | [DOI]
117 Effect of daily drinking of Aloe vera gel extract on plasma total antioxidant capacity and oral pathogenic bacteria in healthy volunteer: a short-term study
Titipong Prueksrisakul, Soranun Chantarangsu, Pasutha Thunyakitpisal
Journal of Complementary and Integrative Medicine. 2015; 12(2)
[Pubmed] | [DOI]
118 In vitro assessment of the prebiotic potential of Aloe vera mucilage and its impact on the human microbiota
Beatriz Gullón,Patricia Gullón,Freni Tavaria,José Luis Alonso,Manuela Pintado
Food Funct.. 2015; 6(2): 525
[Pubmed] | [DOI]
119 Ethnomedicinal plants used by traditional healers of North Tripura district, Tripura, North East India
Prakash Roy Choudhury,Manabendra Dutta Choudhury,Sanjoy Singh Ningthoujam,Dipan Das,Deepa Nath,Anupam Das Talukdar
Journal of Ethnopharmacology. 2015; 166: 135
[Pubmed] | [DOI]
120 Dietary Aloe vera supplementation on growth performance, some haemato-biochemical parameters and disease resistance against Streptococcus iniae in tilapia (GIFT)
Ndakalimwe Naftal Gabriel,Jun Qiang,Jie He,Xin Yu Ma,Mathew D. Kpundeh,Pao Xu
Fish & Shellfish Immunology. 2015;
[Pubmed] | [DOI]
121 Topical application of baby- and adult-aloe on ultraviolet B irradiated mouse skin with metabolite profiling
Hye Min Park,Eunjung Moon,Sarah Lee,Sun Yeou Kim,Seon-Gil Do,Jinwan Kim,Kwang-Hyeon Liu,Choong Hwan Lee
Metabolomics. 2015;
[Pubmed] | [DOI]
122 Host reaction of Aloe vera infected by Meloidogyne incognita and M. javanica in Crete Island (Greece)
Juan E. Palomares-Rius,Pablo Castillo,Hava Rapoport,Antonio Archidona-Yuste,Emmanuel A. Tzortzakakis
European Journal of Plant Pathology. 2015;
[Pubmed] | [DOI]
123 Impact of Nutritional Counselling on Nutritional Status of Postmenopausal Women
Gurpreet Kaur,Paramjit Chawla
Food and Nutrition Sciences. 2015; 06(04): 429
[Pubmed] | [DOI]
124 Aloe vera for prevention and treatment of infusion phlebitis
Guo Hua Zheng, Liu Yang, Hai Ying Chen, Jian Feng Chu, Lijuan Mei
Cochrane Database of Systematic Reviews. 2014; 2017(3)
[Pubmed] | [DOI]
125 Biosynthesis of silver nanoparticles from Aloe vera leaf extract and antifungal activity against Rhizopus sp. and Aspergillus sp.
Shreya Medda,Amita Hajra,Uttiya Dey,Paulomi Bose,Naba Kumar Mondal
Applied Nanoscience. 2014;
[Pubmed] | [DOI]
126 Genetic relationship of Aloe vera æSaengjangæ, a new forma, based on cpDNA and ITS sequence variation
Krishnamoorthy Srikanth,Seon Il Jang,Sung Soo Whang
Korean Journal of Plant Taxonomy. 2014; 44(4): 250
[Pubmed] | [DOI]
127 Aloe vera: a review update on advancement ofin vitroculture
Saikat Gantait,Uma Rani Sinniah,Prakash Kanti Das
Acta Agriculturae Scandinavica, Section B - Soil & Plant Science. 2014; : 1
[Pubmed] | [DOI]
128 In vitro Micropropagation of Ere Meraat (Aloe percrassa Tod.) Using Explants from Offsets
Haftom Baraki Abraha,Desta Berhe Sbhatu,Manikandan Muthuswamy
Asian Journal of Plant Sciences. 2014; 13(2): 66
[Pubmed] | [DOI]
129 Clinical efficacy of new aloe vera- and myrrh-based oral mucoadhesive gels in the management of minor recurrent aphthous stomatitis: a randomized, double-blind, vehicle-controlled study
Ghada Mansour,Soliman Ouda,Ahmed Shaker
Journal of Oral Pathology & Medicine. 2013; : n/a
[Pubmed] | [DOI]
130 Aloe vera herbal dentifrices for plaque and gingivitis control: a systematic review
K Dhingra
Oral Diseases. 2013; : n/a
[Pubmed] | [DOI]
131 Bioresources in the pharmacotherapy and healing of burns: A mini-review
Silva Vujanovic,Josko Vujanovic
Burns. 2013; 39(6): 1031
[Pubmed] | [DOI]
132 The natural medications for wound healing - Curcumin, Aloe-Vera and Ginger - do not induce a significant effect on the migration kinematics of cultured fibroblasts
Topman, G. and Lin, F.-H. and Gefen, A.
Journal of Biomechanics. 2013; 46(1): 170-174
[Pubmed]
133 The natural medications for wound healing – Curcumin, Aloe-Vera and Ginger – do not induce a significant effect on the migration kinematics of cultured fibroblasts
Gil Topman,Feng-Huei Lin,Amit Gefen
Journal of Biomechanics. 2013; 46(1): 170
[Pubmed] | [DOI]
134 Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages
Marietta M. Budai,Aliz Varga,Sándor Milesz,József Tozsér,Szilvia Benko
Molecular Immunology. 2013; 56(4): 471
[Pubmed] | [DOI]
135 Protective value of Aloe vera extract against ?-irradiation-induced some biochemical disorders in rats
A.S. Nada,A.M. Hawas,Z.A. Youssef,N.E. Amin
Journal of Radiation Research and Applied Sciences. 2013;
[Pubmed] | [DOI]
136 Preparation and Characterization of Aloe Vera Blended Collagen-Chitosan Composite Scaffold for Tissue Engineering Applications
Panneerselvam Jithendra,Abraham Merlin Rajam,Thambiran Kalaivani,Asit Baran Mandal,Chellan Rose
ACS Applied Materials & Interfaces. 2013; 5(15): 7291
[Pubmed] | [DOI]
137 Cosmetologia della pelle nera
F. Ly,M. Ndiaye,A. Diop,B.A. Diatta,M. Diallo
EMC - Cosmetologia Medica e Medicina degli Inestetismi Cutanei. 2013; 10(1): 1
[Pubmed] | [DOI]
138 Complement activation and inhibition in wound healing
Cazander, G. and Jukema, G.N. and Nibbering, P.H.
Clinical and Developmental Immunology. 2012; 2012(534291)
[Pubmed]
139 HPTLC profile of aqueous extract of different chromatographic fractions of Aloe barbadensis Miller
Ojha, N.K. and Kumar, A.
Asian Pacific Journal of Tropical Disease. 2012; 2(SUPPL.1): S104-S108
[Pubmed]
140 Herbs-Are they Safe Enough? An Overview
Singh, D. and Gupta, R. and Saraf, S.A.
Critical Reviews in Food Science and Nutrition. 2012; 52(10): 876-898
[Pubmed]
141 The effect of Aloe vera leaf gel on fatty streak formation in hypercholesterolemic rabbits
Dana, N. and Javanmard, S.H. and Asgary, S. and Asnaashari, H. and Abdian, N.
Journal of Research in Medical Sciences. 2012; 17(5): 439-442
[Pubmed]
142 Morphological and physiological characters of Aloe vera subjected to saline water irrigation
Rahimi-Dehgolan, R. and Sarvestani, Z.T. and Rezazadeh, S.A. and Dolatabadian, A.
Journal of Herbs, Spices and Medicinal Plants. 2012; 18(3): 222-230
[Pubmed]
143 Anti-atherosclerotic effects of Aloe vera in hypercholesterolemic rabbits
Dana, N. and Haghjooy Javanmard, S. and Asgary, S. and Asnaashari, H. and Abdian, N.
Journal of Babol University of Medical Sciences. 2012; 14(4): 37-44
[Pubmed]
144 Efficacy of Aloe vera/olive oil cream versus betamethasone cream for chronic skin lesions following sulfur mustard exposure: A randomized double-blind clinical trial
Panahi, Y. and Davoudi, S.M. and Sahebkar, A. and Beiraghdar, F. and Dadjo, Y. and Feizi, I. and Amirchoopani, G. and Zamani, A.
Cutaneous and Ocular Toxicology. 2012; 31(2): 95-103
[Pubmed]
145 A herbal cream consisting of Aloe vera, Lavandulastoechas, and Pelargonium roseum as an alternative for silver sulfadiazine in burn management
Panahi, Y. and Beiraghdar, F. and Akbari, H. and Bekhradi, H. and Taghizadeh, M. and Sahebkar, A.
Asian Biomedicine. 2012; 6(2): 273-278
[Pubmed]
146 Aloe vera Gel: Structure, chemical composition, processing, biological activity and importance in pharmaceutical and food industry [El gel de aloe vera: Estructura, composición química, procesamiento, actividad biológica e importancia en la industria farmacéutica y alimentaria]
Domínguez-Fernández, R.N. and Arzate-Vázquez, I. and Chanona-Pérez, J.J. and Welti-Chanes, J.S. and Alvarado-González, J.S. and Calderón-Domínguez, G. and Garibay-Febles, V. and Gutíerrez-López, G.F.
Revista Mexicana de Ingeniera Qumica. 2012; 11(1): 23-43
[Pubmed]
147 Herbs–Are they Safe Enough? An Overview
Divya Singh,Rajiv Gupta,Shubhini A. Saraf
Critical Reviews in Food Science and Nutrition. 2012; 52(10): 876
[Pubmed] | [DOI]
148 Morphological and Physiological Characters ofAloe veraSubjected to Saline Water Irrigation
Ramin Rahimi-Dehgolan,Zeinolabedin Tahmasebi Sarvestani,Shams Ali Rezazadeh,Aria Dolatabadian
Journal of Herbs, Spices & Medicinal Plants. 2012; 18(3): 222
[Pubmed] | [DOI]
149 Complement Activation and Inhibition in Wound Healing
Gwendolyn Cazander,Gerrolt N. Jukema,Peter H. Nibbering
Clinical and Developmental Immunology. 2012; 2012: 1
[Pubmed] | [DOI]
150 Efficacy of <i>Aloe vera</i>/olive oil cream versus betamethasone cream for chronic skin lesions following sulfur mustard exposure: a randomized double-blind clinical trial
Yunes Panahi, Seyyed Masoud Davoudi, Amirhossein Sahebkar, Fatemeh Beiraghdar, Yahya Dadjo, Iraj Feizi, Golnoush Amirchoopani, Ali Zamani
Cutaneous and Ocular Toxicology. 2011; : 1
[VIEW] | [DOI]
151 Biochemical studies of Aloe vera (Aloe barbadensis Miller) gel of the field grown and micropropagated plants at different developmental stages
Varindra Pandhair, J. Diviya, S. Joginder, S. S. Gosal
Journal of Plant Biochemistry and Biotechnology. 2011;
[VIEW] | [DOI]
152 Hypoglycemic and hypolipidemic effect of Aloe vera L. in non-insulin dependent diabetics
Monika Choudhary, Anita Kochhar, Jaswinder Sangha
Journal of Food Science and Technology. 2011;
[VIEW] | [DOI]
153 Aloe vera gel alleviates cardiotoxicity in streptozocin-induced diabetes in rats
Jaina, N., Vijayaraghavana, R., Panta, S.C., Lomasha, V., Alib, M.
Journal of Pharmacy and Pharmacology. 2010; 62(1): 115-123
[Pubmed]
154 Effect of Aloe Vera (Aloe barbadensis) gel extract on repolarization state of myocardium in albino rat
Kumar, P. and Verma, S. and Singh, S. and Tiwari, S. and Khan, M.Y.
African Journal of Pharmacy and Pharmacology. 2010; 4(12): 885-889
[Pubmed]
155 Herbal treatment for lichen planus
Yarnell, E. and Abascal, K.
Alternative and Complementary Therapies. 2010; 16(4): 217-222
[Pubmed]
156 Bioactive chromone derivatives - structural diversity
Machado, N.F.L. and Marques, M.P.M.
Current Bioactive Compounds. 2010; 6(2): 76-89
[Pubmed]
157 Aloe vera: A plant for many uses
Christaki, E.V. and Florou-Paneri, P.C.
Journal of Food, Agriculture and Environment. 2010; 8(2): 245-249
[Pubmed]
158 Herbal treatment for lichen planus
Yarnell, E., Abascal, K.
Alternative and Complementary Therapies. 2010; 16(4): 217-222
[Pubmed]
159 Bioactive chromone derivatives - structural diversity
Machado, N.F.L., Marques, M.P.M.
Current Bioactive Compounds. 2010; 6(2): 76-89
[Pubmed]
160 Aloe vera: A plant for many uses
Christaki, E.V., Florou-Paneri, P.C.
Journal of Food, Agriculture and Environment. 2010; 8(2): 245-249
[Pubmed]
161 Aloe vera gel alleviates cardiotoxicity in streptozocin-induced diabetes in rats
Neeti Jain,Rajagopalan Vijayaraghavan,Satish Chandra Pant,Vinay Lomash,Mohammed Ali
Journal of Pharmacy and Pharmacology. 2010; 62(1): 115
[Pubmed] | [DOI]
162 Herbal Treatment for Lichen Planus
Eric Yarnell,Kathy Abascal
Alternative and Complementary Therapies. 2010; 16(4): 217
[Pubmed] | [DOI]
163 Revision of aloe vera (Barbadensis Miller) in actual dermatology | [Revisión de la aloe vera (Barbadensis Miller) en la dermatología actual]
Ferraro, G.M.
Revista Argentina de Dermatologia. 2009; 90(4): 218-223
[Pubmed]
164 Revision of aloe vera (Barbadensis Miller) in actual dermatology [Revisión de la aloe vera (Barbadensis Miller) en la dermatología actual]
Ferraro, G.M.
Revista Argentina de Dermatologia. 2009; 90(4): 218-223
[Pubmed]



 
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