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Herpes zoster ophthalmicus (HZO) is a disease of elderly affective individuals in the sixth or seventh decades of life. It rarely results in extraocular muscle palsy. We here with report two cases of HZO associated with cranial nerve palsies who tested positive for HIV. Case I had third, fourth and sixth nerve palsies whereas case 2 had third nerve palsy with papillary movement affected in association with ophthalmic herpes zoster. A course of systemic acyclovir and steroids led to complete recovery in the first case and partial recovery in the second case.