Indian Journal of Dermatology
  Publication of IADVL, WB
  Official organ of AADV
Indexed with Science Citation Index (E) , Web of Science and PubMed
 
Users online: 4825  
Home About  Editorial Board  Current Issue Archives Online Early Coming Soon Guidelines Subscriptions  e-Alerts    Login  
    Small font sizeDefault font sizeIncrease font size Print this page Email this page
Year : 2004  |  Volume : 49  |  Issue : 2  |  Page : 55-61

Experimental Skin Graft In Hairless Descendants Of Mexican Hairless Dogs



Correspondence Address:
Tohru Kimura


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

In order to enhance the successful rate of skin transplantation, tie-over method and occlusive dressings were investigated using the skin of hairless dogs. Tie-over method had no accelerative effects of the skin grafting of hairless dogs. In contrast, at 2 weeks after grafting, the graft skin has taken well under the moist environment. The hydrocolloid dressing accelerated wound healing in the donor sites. In both the graft and the donor sites, wound contraction and crust formation were not found throughout the study, although the skin of hairless dogs lagged considerably behind that of other haired dogs in wound healing. At 2 weeks after the skin grafting, histologically, the epidermis of the grafts showed thickening and irregular hyperplasia with prominent rete ridges, suggesting a relatively high rate of cell proliferation and/or differentiation. In the dermis, the formation of granulation tissues was found, and neovascularization was obscure. At 4 weeks after skin grating, the epidermis remained thick and hair follicles with well-developed sebaceous glands were observed in some portions. In the donor sites, at 2 weeks after the treatment with hydrocolloid dressing, there was reepithelialization arising from the wound margin. In the dermis, dense granulation tissues containing many fibroblasts and collagen fibers were formed. At 4 weeks after the treatment, the regenerated skin exhibited a remarkable thickening of the epidermis, especially the granular layer, and well-developed rete ridges. These findings revealed that the treatment with the hydrocolloid dressing was a valuable measure in accelerating graft take and wound healing in the donor sites of hairless dogs.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed826    
    Printed42    
    Emailed0    
    PDF Downloaded67    
    Comments [Add]    

Recommend this journal