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Primary tuberculosis of the glans penis is extremely rare. We report a case in a 47 years old man who presented with an ulcer over glans, which mimicked malignancy. The diagnosis of tuberculosis was confirmed by biopsy and response to antituberculous chemotherapy. There was no co- exiting tuberculous infection elsewhere. The wife of the patient was under treatment for pulmonary tuberculosis. The possibility of acquiring the disease following sexual contact could not be ruled out. The importance of biopsy in the diagnosis of chronic genital ulcer is emphasized.