Indian Journal of Dermatology
  Publication of IADVL, WB
  Official organ of AADV
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Year : 2001  |  Volume : 46  |  Issue : 2  |  Page : 83-85

Role Of Combination Of Multiple Herbal Drugs (Septilin) In The Prophylaxis Of Diabetic Foot Ulcer - A Double Blind Trial

Correspondence Address:
S.K Singh

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Infections, ischaemia and neuropathy are the major threats to diabetic foot apart from aerobic gram-negative organisms, anaerobic bacteria such as bacteriodes species play an important role in causing infection. Septilin, a polyherbal formulation with various constituents having antimicrobial, anti-inflammatory and immunomodulatory properties was evaluated in patients with diabetic foot ulcers. Septilin was administered at a dose of 2 tablets twice daily for 12 weeks. After 12 weeks of treatment, about 75% of the patients in group A had sterile would swab culture and 24% (approx) had some growth of E. coil and proteus. There was no growth of kelbsiella in this group. In group B. about 50% had recurrence of gram-negative infection and about 28% of patients showed gram-positive isolate in addition to gram-negative culture. Two patients in group B were dropped from the study due to high blood sugar levels.

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