PK Kaviarasan Dept. of Dermatology and STD; Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) Pondichery 605006 India
Source of Support: None, Conflict of Interest: None
ABSTRACT: An increased colonization of Malassezia furfur organism has been reported in patients with HIV infection. Pityriasis versicolor and pityrosporum folliculitis arise from overgrowth of M. furfur. It is also thought to have a significant role in the pathogenesis of seborrheic dermatitis and is one of the earliest clinical markers of HIV infection. The present study was to note the occurrence and significance of these infections in HIV infected. The occurrence of pityrosporum infection was 13.5 percent (25 cases amongst 185 HIV seropositive patients) in HIV infected cases in our study. Mean Age of the affected patients was 31.7 Years and male to female ratio was 1.5:1. The main mode of acquisition of HIV infection was heterosexual (19 cases). Tinea versicolor was seen in 10 (40 percent) cases, seborrheic dermatitis in 14(56 percent) and pityrosporum folliculitis in 4(16 percent) cases. seborrheic dermatitis was found to be more explosive in onset and involving extensive areas with severe inflammation. Extensive tinea versicolor and seborrheic dermatitis were seen in three cases with pityrosporum infections. Nine of the pityrosporum infections were observed in HIV Group IV, which is equivalent of AIDS. To conclude, seborrheic dermatitis in patients with HIV/AIDS may have some unique features and may be used as a clinical marker of AIDS.