N Khan J. N. Medical College, Aligarh Muslim University, Aligarh-202001
Source of Support: None, Conflict of Interest: None
ABSTRACT: Serum Cholinesterase (CHE) and Lactate Dehydrogenase (LDH) levels were estimated in 25 healthy controls and 40 cases of malignancy skin. The method of enzyme estimations were colorimetric. Results depicted a significant fall in serum ChE and a significant rise in serum LDH levels as compared to controls. Of the two enzyme serum ChE was found to be more helpful as it exhibited a rough correlation with tumour size and was also able to differentiate the metastatic from the non metastatic tumours. However, both the enzymes showed no relationship with the degree of differentiation of tumours. It is suggested that determination of these two enzymes may serve as a simple diagnostic tool in malignancy skin.