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Figure 2: The apoptotic rate of HaCaT cells of different groups. (a) The apoptotic rate of the control group was 2.6%, vascular endothelial growth factor group was 3%, semaphorin 3A group was 22.4%, vascular endothelial growth factor + semaphorin 3A was 10.8%, acitretin group was 22.9%, and vascular endothelial growth factor + acitretin was 15.6%. (b) The control group and vascular endothelial growth factor group had no obvious change on apoptosis. Semaphorin 3A, vascular endothelial growth factor + semaphorin 3A, acitretin, and vascular endothelial growth factor + acitretin increased the apoptotic rate of HaCaT cells. *P < 0.05, **P < 0.005 versus control group. #P < 0.05, ##P < 0.005 versus vascular endothelial growth factor exposed groups

Figure 2: The apoptotic rate of HaCaT cells of different groups. (a) The apoptotic rate of the control group was 2.6%, vascular endothelial growth factor group was 3%, semaphorin 3A group was 22.4%, vascular endothelial growth factor + semaphorin 3A was 10.8%, acitretin group was 22.9%, and vascular endothelial growth factor + acitretin was 15.6%. (b) The control group and vascular endothelial growth factor group had no obvious change on apoptosis. Semaphorin 3A, vascular endothelial growth factor + semaphorin 3A, acitretin, and vascular endothelial growth factor + acitretin increased the apoptotic rate of HaCaT cells. *<i>P</i> < 0.05, **<i>P</i> < 0.005 versus control group. <sup>#</sup><i>P</i> < 0.05, <sup>##</sup><i>P</i> < 0.005 versus vascular endothelial growth factor exposed groups