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Figure 4: (a) Biopsy from a papule showing peripheral rim of de-pigmentation revealed melanocytic neoplasm with flattened epidermis made up of nests of neoplastic melanocytes in upper dermis and within the dilated capillaries in the deep dermis. (H and E, ×5), (b) Irregular shaped small nests of atypical melanocytes at dermo-epidermal junction with epidermal flattening overlying the dermal nests. (H and E, ×10), (c) Moderately dense superficial peri-vascular lymphocytic and plasma cellular infiltrate underlying the dermal nests. (H and E, ×10), (d) Irregular shaped small nests at dermo-epidermal junction with numerous solitary melanocytes scattered throughout the surrounding epidermis including the stratum corneum. (H and E, ×20)

Figure 4: (a) Biopsy from a papule showing peripheral rim of de-pigmentation revealed melanocytic neoplasm with flattened epidermis made up of nests of neoplastic melanocytes in upper dermis and within the dilated capillaries in the deep dermis. (H and E, ×5), (b) Irregular shaped small nests of atypical melanocytes at dermo-epidermal junction with epidermal flattening overlying the dermal nests. (H and E, ×10), (c) Moderately dense superficial peri-vascular lymphocytic and plasma cellular infiltrate underlying the dermal nests. (H and E, ×10), (d) Irregular shaped small nests at dermo-epidermal junction with numerous solitary melanocytes scattered throughout the surrounding epidermis including the stratum corneum. (H and E, ×20)