Indian Journal of Dermatology
ORIGINAL ARTICLE
Year
: 2017  |  Volume : 62  |  Issue : 5  |  Page : 486--490

Hand, foot and mouth disease in West Bengal, India: A preliminary report on clinicovirological trend over 3 successive years (2013–2015)


Nilendu Sarma1, Sayantani Chakraborty2, Abira Dutta3, Provash Chandra Sadhukhan3 
1 Department of Dermatology, Dr. B C Roy Post Graduate Institute of Pediatric Sciences, Kolkata - 700 010, West Bengal, India
2 Department of Dermatology, R G Kar Medical College, Kolkata - 700 010, West Bengal, India
3 ICMR Virus Unit, I.D & B.G Hospital Campus, GB-4, Beliaghata, Kolkata - 700 010, West Bengal, India

Correspondence Address:
Nilendu Sarma
Associated Professor and Head P N Colony, Sapui Para, Bally, Howrah - 711 227, West Bengal
India

Introduction: Hand, foot, and mouth disease (HFMD), an enteroviral disease has emerged as a major emerging infection in India. This is caused most commonly by enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) but can also be due to CVA4-10, CVA24, CVB2-5, and echovirus 18 (Echo18). Virological analysis of the cases of HFMD has been infrequently done in India. West Bengal is one of the worst affected states in India. Objective: To document the clinical and etiological aspect, the changing patterns and clinic-virological correlation. Method: a total of 62 samples of throat swab were collected from affected children over 3 successive years in Kolkata, West Bengal, India. Result: Five cases had a previous history of HFMD during the last 1–5 years. Fever was usually of mild degree (highest 102°C). There was no apparent correlation between fever of >100°C and a positive test. There was no correlation of viral strain and clinical severity. A test positive for the Viral RNA was noted among 64.51% (40/62) cases. Multiple strains were characteristically present in each year. CVA6, EV71 were found in 2013, CVA6, EV71 in 2014, and CVA6, CVA16 in 2015. Conclusion: Presence of multiple strains explained the frequent occurrence of relapses. We expect this small study will serve as an important document for all future studies on HFMD.


How to cite this article:
Sarma N, Chakraborty S, Dutta A, Sadhukhan PC. Hand, foot and mouth disease in West Bengal, India: A preliminary report on clinicovirological trend over 3 successive years (2013–2015).Indian J Dermatol 2017;62:486-490


How to cite this URL:
Sarma N, Chakraborty S, Dutta A, Sadhukhan PC. Hand, foot and mouth disease in West Bengal, India: A preliminary report on clinicovirological trend over 3 successive years (2013–2015). Indian J Dermatol [serial online] 2017 [cited 2020 Aug 14 ];62:486-490
Available from: http://www.e-ijd.org/article.asp?issn=0019-5154;year=2017;volume=62;issue=5;spage=486;epage=490;aulast=Sarma;type=0