Indian Journal of Dermatology
DERMATOPATHOLOGY ROUND
Year
: 2013  |  Volume : 58  |  Issue : 5  |  Page : 366--368

Primary cutaneous diffuse large B-cell lymphoma of the upper limb: A fascinating entity


Manoj Madakshira Gopal, Ajay Malik 
 Department of Pathology, Armed Forces Medical College, Pune, Maharashtra, India

Correspondence Address:
Manoj Madakshira Gopal
Department of Pathology, Armed Forces Medical College, Pune - 411 040, Maharashtra
India

Primary cutaneous lymphomas are defined as lymphoid neoplasms that present themselves clinically on the skin and do not have extra-cutaneous disease, when the diagnosis is made or even after 6 months of the diagnosis. Primary cutaneous lymphomas of B-cells are less frequent than lymphomas of T-cells. Primary B-cell lymphomas have a better prognosis than secondary B-cell lymphomas. Primary B-cell cutaneous lymphomas are classified into five types according to the World Health Organization and European Organization for Research and Treatment of Cancer classification. The primary diffuse large B-cell cutaneous lymphoma - leg type corresponds to approximately 5-10% of the B-cell cutaneous lymphomas. It is predominantly seen in elderly people and has a female preponderance. Skin lesions can be single, multiple, and even grouped. A 5-year survival rate ranges from 36 to 100% of the cases. The expression of Bcl-2, presence of multiple lesions, and involvement of both the upper limbs lead to a worse prognosis. Very few cases have been described in the literature.


How to cite this article:
Gopal MM, Malik A. Primary cutaneous diffuse large B-cell lymphoma of the upper limb: A fascinating entity.Indian J Dermatol 2013;58:366-368


How to cite this URL:
Gopal MM, Malik A. Primary cutaneous diffuse large B-cell lymphoma of the upper limb: A fascinating entity. Indian J Dermatol [serial online] 2013 [cited 2020 Aug 4 ];58:366-368
Available from: http://www.e-ijd.org/article.asp?issn=0019-5154;year=2013;volume=58;issue=5;spage=366;epage=368;aulast=Gopal;type=0