Year : 2009 | Volume
: 54 | Issue : 4 | Page : 323--329
Photo-stimulatory effect of low energy helium-neon laser irradiation on excisional diabetic wound healing dynamics in wistar rats
Arun G Maiya, Pramod Kumar, B Shivananda Nayak
Department of Physiotherapy, Manipal Medical College, Manipal, India
Background: Generally, the significances of laser photo stimulation are now accepted, but the laser light facilitates wound healing and tissue repair remains poorly understood. Aims: We have examined the hypothesis that the laser photo stimulation can enhance the collagen production in diabetic wounds using the excision wound model in the Wistar rat model. Methods: The circular wounds were created on the dorsum of the back of the animals. The animals were divided into two groups. The study group (N = 24) wound was treated with 632.8 nm He-Ne laser at a dose of 3-9J/cm 2 for 5 days a week until the wounds healed completely. The control group was sham irradiated.
Result: A significant increase in the hydroxyproline content and reduction in the wound size were observed in the study group. The pro-healing actions seem to be due to increased collagen deposition as well as better alignment and maturation. Conclusion: The biochemical analysis and clinical observation suggested that 3-6 J/cm 2 laser photo stimulation facilitates the tissue repair process by accelerating collagen production in diabetic wound healing.
Arun G Maiya
Department of Physiotherapy, Manipal University, Manipal - 576 104
|How to cite this article:|
Maiya AG, Kumar P, Nayak B S. Photo-stimulatory effect of low energy helium-neon laser irradiation on excisional diabetic wound healing dynamics in wistar rats.Indian J Dermatol 2009;54:323-329
|How to cite this URL:|
Maiya AG, Kumar P, Nayak B S. Photo-stimulatory effect of low energy helium-neon laser irradiation on excisional diabetic wound healing dynamics in wistar rats. Indian J Dermatol [serial online] 2009 [cited 2020 Jan 24 ];54:323-329
Available from: http://www.e-ijd.org/article.asp?issn=0019-5154;year=2009;volume=54;issue=4;spage=323;epage=329;aulast=Maiya;type=0