Indian Journal of Dermatology

Year
: 1999  |  Volume : 44  |  Issue : 4  |  Page : 187--190

Intravenous Dexamethasone Pulse Therapy For Extensive Alopecia Areata


Devinder Mohan Thappa 
 

Correspondence Address:
Devinder Mohan Thappa


Patient with extensive alopecia areata (>30% scalp involvement) were given 32mg of dexamethasone in 200 ml of 5% dextrose intravenously on three consecutive days (total 96mg) every four weeks. Response was quantified as 1 to 25%, 25% to 50%, 50 to 75% and 75 to 100% of terminal hair growth by mapping and serial photographs. They were examined monthly for side effects of steroids. Six patients (5 male and 1 female) with a mean age of 32 years were recruited. They had alopecia areata for a period ranging from 3 months to 2.5 years. All the six cases did not show further worsening of alopecia after 3 pulses. However, two of them showed less than 25% hair growth after 4 pulses and did not turn up for follow up. In 2 cases, 25 to 50% growth was observed an 50 to 75% growth was seen in 2 patients (one of them with ophiasic pattern) after 6 pulses. The results were cosmetically acceptable for three of them. No adverse effect to steroids was encountered and the patients are still under follow up. The preliminary results show that dexamethasone pulse therapy is safe and effective for extensive alopecia areata.


How to cite this article:
Thappa D. Intravenous Dexamethasone Pulse Therapy For Extensive Alopecia Areata.Indian J Dermatol 1999;44:187-190


How to cite this URL:
Thappa D. Intravenous Dexamethasone Pulse Therapy For Extensive Alopecia Areata. Indian J Dermatol [serial online] 1999 [cited 2020 Aug 11 ];44:187-190
Available from: http://www.e-ijd.org/article.asp?issn=0019-5154;year=1999;volume=44;issue=4;spage=187;epage=190;aulast=Thappa;type=0