Peripheral T-cell Count in Sixty Cases of Cutaneous Vasculitis

Clinically diagnosed 60 cases of cutaneous vasculitis (CV) were collected from Dermato-venereology Department. T-cell count in the peripheral blood, a marker of cell-mediated immunity, was done in all the cases by Thomson Method 1977. Statistically significant increase in peripheral T-lymphocytes was seen in 15/60 (25%) cases of CV.

A Comparison of the Efficacy of Cetirizine and Terfenadine in Chronic Idiopathic Urticaria

In a 10 d, double blind, randomized, parallel study, the efficacy of cetirizine and terfenadine was compared in 30 patients with chronic idiopathic urticaria. Subjects were randomly divided into two patient groups of 15 each. The first group was given cetirizine (10 mg once daily) and the second terfenadine (120 mg once daily). Cetirizine proved to be more effective than terfenadine in controlling urticaria symptoms. In fact, the score of the investigators' overall assessment was significantly lower in cetirizine-treated group than in terfenadine-treated group. Moreover, patients' evaluation of symptoms assessed on a four point scale showed a better improvement in the cetirizine group. The number and severity of side-effects were similar in both the groups.

Pattern of Cutaneous Tuberculosis

The incidence, pattern and clinical types of cutaneous tuberculosis, along with responses to treatment, observed amongst our total dermatology outpatients over the past three years are projectd in this study.

Comparative Evaluation of Topical Sodium Fusidate Cream in Common Pyodermas with Topical Gentamicin Ointment and Systemic Antibiotics

One hundred cases of common pyodermas consisting of four groups, namely impetigo, Bockhart's impetigo, furunculosis and chronic folliculitis were taken. Each group containing twenty five cases were divided again into three subgroups. From each group, 15 were treated with 2% Sodium fusidate cream, 5 were with 0.1% Gentamycin sulphate cream and the rest 5 with systemic Erythromycin stearate. In the group of Impetigo, Bockhart's Impetigo and Furunculosis, topical Sodium fusidate cream showed excellent result, better than Gentamycin topical and equal to that of systemic Erythromycin stearate.

Clinicopathological Determinants of Indeterminate Leprosy

Thirty untreated patients, clinically diagnosed as indeterminate leprosy (IL), were studied for history, examination of the patch, peripheral and local nerves and investigated for slit skin smears from ear, nose and lesion proper for bacterial index, lepromin test (using Dharmendra antigen), skin biopsy, routine hemogram and skiagrams of chest. IL was found to be principally prevalent (26.7%) among the boys. Mostly single lesion (83.3%) involving right upper extremity (26.7%) of an average size of 3 mm with frequent diminution of temperature sensation (90%) alongwith thickening of right ulnar nerve (20%) was noted. Bacterial index was '0' and majority showed a negative lepromin reaction. Histopathology revealed perineural (86.7%), perivascular linear and star-shaped mononuclear cellular infiltration. Acid-fast bacilli were noted in majority cases by special stain in serial sections.

Scleredema of Buschke

A 19 year old male patient presented with typical lesions of scleredema. The lesions were preceded by acute febrile illness.

Congenital Morphea

A 2 month old male infant born with a classical plaque of Morphea over his abdomen is presented here for its unusual congential occurrence.

Trichoadenoma of Nikolowski

A case of trichoadenoma developing on the shaft of penis is reported in a young male. Histology revealed numerous horn cysts, each surrounded by eosinophilic epithelial cells. Its differentiating features from trichoepithelioma, histopathologically, are described.

Angiolymphoid Hyperplasia with Eosinophilia

A 28 year old female presented with multiple, firm, nodular lesions on the back of left pinna and adjoining skull with severe itching and eczematous changes of left pinna. Histopathology revealed picture consistent with angiolymphoid hyperplasia. The nodules persisted for 3 years and surgically excised.

Verrucous Haemangioma

A 15 year old boy presented with a verrucous plaque on left leg above the ankle. There was history of bleeding on trauma on several occasions. The lesion was present at birth as an erythematous macule. Histopathological examination established the diagnosis of verrucous haemangioma. Surgical excision has been done.