Seventy Five cases of exfoliative dermatitis

A study of 75 cases of exfoliative dermatitis showed a male preponderance (M:F=4.77:1) with highest frequency of occurrence in the fifth and sixth decades. Cutaneous ailments were responsible for 64% of cases, among which psoriasis was the commonest disease followed by various types of eczema. The syndrome was caused by drugs in 12% of the cases and malignancy in 2.67%. In 21.33% of patients the cause remained undetermined. The systemic changes and the laboratory findings are described.

Evaluation of the efficacy of topical doxepin, alone or in Combination with topical corticosteroid, in the management of atopic dermatitis

In this prospective study, sixty patients, 28 male and 21 female aged 7 to 48 (mean 12.5) years, were divided into 3 equal groups. Patients in gr I applied 5% doxepin hydrochloride cream over the eczematous lesions twice daily for 2 weeks. Group II patients were treated with clobetasol propionate (0.05%) cream twice daily for 2 weeks. In gr III, the patients received topical clobetasol propionate twice daily for the first week and doxepin hydrochioride cream twice daily for the 2nd week. The improvement was measured by 'subjective symptom' (SS) and 'objective sign' (OS) scoring systems. Improvement in SS was maximum in gr III, moderate in gr I and mild in gr II. Improvement in OS was maximum in gr III followed by gr II and gr I. Lichenified lesions showed no improvement. Somnolence and stinging at the local site were the adverse effects complained by 8(40%) and 3(15%) patients in gr I respectively, 2(10%) patients had both in gr III.

Corneal hypoaesthesia in various types of leprosy

Four hundred leprosy patients comprising of 140 lepromatous leprosy, 72 borderline and 188 tuberculoid leprosy patients were examined for corneal hypoaesthesia. Among them, 25 cases of lepromatous, 4 of borderline and 21 tuberculoid patients showed corneal hypoaesthesia. Upper temporal corneal area was most frequently affected. Stress is laid on health education and timely intervention.

Milia en plaque - an unusual presentation

Milia en plaque, an unusual clinical variant of milia, has been reported mainly in the post auricular area. We report a case of milia en plaque over an unusual site i.e. over the angle of the mouth present over lesions of pityriasis alba.

Trichotillomania in a child

A case of trichotillomania in a female child is presented. Unusual features in this case are early age of onset, total alopecia of the scalp and plucking the hair of the animals.

Genetic icthyosis and chronic dermatophytosis - a clinical diagnostic dilemma

Chronic dermatophytosis caused by Trichophyton rubrum in two patients with genetic ichthyosis is being reported for its atypical manifestations leading to difficulties in diagnosis and management.

Unusually rapid response in psoriasis treated with PUVA

Two cases of psoriasis under PUVA therapy presented for its unusual rapid response with quick clearance of lesions within three weeks.

Reinfection and bilateral infection : Two rare manifestations of sporotrichosis

The localization of sporotrichosis is determined by the site of dermal injury by means of which the infective spores are introduced into subcutaneous tissue, but the reports of reinfection or bilateral infection are extremely rare. Although the probability of such occurrence is high in endemic areas, the rare incidence may be due to acquired host defence, a subject of much speculation. Two such rare cases are presented and some reports of cross infections of the disease are reviewed.

Late onset juvenile xanthogranuloma

A 19 year old female was seen with multiple skin coloured and hyperpigmented macules, discrete as well as grouped papules and nodules of varying sizes distributed over the face, neck, extensor and flexor aspects of both upper and lower extremities including joints. The trunk was spared. Some of he lesions showed features of spontaneous regression. Investigation confirmed the diagnosis of juvenile xanthogranuloma. Lesions regressed satisfactorily with liquid nitrogen cryotherapy.

Acquired Periungual fibrokeratoma resembling Koenen tumour

A case of periungual fibrokeratoma acquired following blunt trauma to toe, is being descrbied. Its resemblance to Koenen tumour of tuberous sclerosis and other similar lesins is discussed.

Romberg's syndrome

A 16 years old female with focial hemiatrophy and convulsions having sparse right eyebrows and eye lashes, flattening of the nasolabial fold, protrusion of eye ball, and retraction of angle of mouth towards the affected side is reported

Connective tissue naevus

A young adult female patient of connective tissue naevus presented with papules and indurated plaques on both legs and left arm. Histopathology showed increased amount of collagen in the dermis. Osteopoikilosis was absent.

Progressive symmetric erythrokeratoderma

A case of progressive symmetric erythrokeratoderma is reported for its rarity and clinical interest.

Herpes simplex encephalitis

A twenty five year old female patient presented with bilateral grouped vesicular lesions with altered sensorium. It was diagnosed

Mycosis fungoides

A fifty six year old patient developed erythematous macules, papules, annular plaques, nodules, tumours, ulcerated lesions and poikiloderma. After initial difficulty, a diagnosis of mycosis fungoides was finally made on histopathology

Multiple leiomyoma

A case of multiple cutaneous leiomyomas is reported for its uncommon occurrence. This case was associated with osseous and soft tissue hamartoma of right thumb, lipoma on left side of chest and back, hoarseness of voice and lower motor neurone disorder in limbs.

Erythrokeratoderma variabilis

Erythrokeratoderma variabilis in an infant is describes with classical clinical picture and histopathological changes. treatment with combination of tropical retinoids and steroids was observed to be effective.

Fox-Fordyce Disease

A case of Fox-Fordyce in a 21 year old female is reported because of its rarity.