Indian Journal of Dermatology
  Publication of IADVL, WB
  Official organ of AADV
Indexed with Science Citation Index (E) , Web of Science and PubMed
 
Users online: 5693  
Home About  Editorial Board  Current Issue Archives Online Early Coming Soon Guidelines Subscriptions  e-Alerts    Login  
    Small font sizeDefault font sizeIncrease font size Print this page Email this page
CASE REPORT
Year : 2020  |  Volume : 65  |  Issue : 3  |  Page : 217-221

Blastic plasmacytoid dendritic cell neoplasm: Case report and literature overview


1 Center of Postgraduate Medical Education, Novosibirsk National Research State University, Novosibirsk, Russian Federation
2 Center of Postgraduate Medical Education, Novosibirsk National Research State University; Novosibirsk Research Institute of Fundamental and Clinical Immunology, Novosibirsk, Russian Federation
3 Novosibirsk Research Institute of Fundamental and Clinical Immunology, Novosibirsk, Russian Federation
4 Novosibirsk Scientific Research Institute of Tuberculosis, Novosibirsk, Russian Federation

Correspondence Address:
Anastasiia Kolerova
Center of Postgraduate Medical Education, Novosibirsk National Research State University, Pirogova, 630090 Novosibirsk
Russian Federation
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijd.IJD_235_18

Rights and Permissions

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a malignancy with high frequency of skin involvement. A 39-year-old Caucasian female was suffering from weakness, myalgia, and skin eruption, which appeared during treatment of chlamydiosis with antibiotics in July 2016. Based on clinical presentation, laboratory investigations, and histological examination of skin and bone marrow biopsy, a diagnosis of BPDCN with the involvement of skin, bone marrow, and central nervous system was made. The patient was put on acute lymphoblastic leukemia-like chemotherapy and achieved complete remission in November 2016, the eruption regressed. In January 2017, allogeneic bone marrow transplantation from matched sibling was performed. Since May 2017, the cutaneous relapse with loss of CD56 expression has developed. This clinical case demonstrates the importance of laboratory tests. Histological examination helps to clarify a diagnosis of cutaneous lymphoma; however, a specific type of lymphoma needs immunohistochemical analysis. In our case, BPDCN at the initial stage presented like a systemic vasculitis.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed656    
    Printed17    
    Emailed0    
    PDF Downloaded24    
    Comments [Add]    

Recommend this journal