Indian Journal of Dermatology
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CASE REPORT
Year : 2019  |  Volume : 64  |  Issue : 6  |  Page : 493-496

Hydroa vacciniforme-like lymphoma with systemic symptoms: Two case reports


1 Department of Dermatology, Affiliated Hospital of Hebei University of Engineering, Handan 056002, Hebei, China
2 Department of Dermatology, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, China

Correspondence Address:
Guiying Zhang
Department of Dermatology, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijd.IJD_178_18

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Two Chinese children presented with relapsing papules, vesicles, ulcers on the face and limbs with systemic symptoms being caused by mosquito bite. Lesion biopsy revealed atypical lymphocyte in the dermis and subcutis. Immunohistochemistry identified cells as positive for CD3, CD45RO, TIA-1 and EBER. Taken together, both the patients were diagnosed with hydroa vacciniforme-like lymphoma. Two patients showed significant improvement in clinical symptoms after being treated with acyclovir, low dose predisone and IFN-α.


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