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Year : 2017  |  Volume : 62  |  Issue : 1  |  Page : 108-110
Solitary subcutaneous nodule over the right elbow


1 Department of Dermatology, Venereology and Leprology, JIPMER, Puducherry, India
2 Department of Pathology, JIPMER, Puducherry, India

Date of Web Publication10-Jan-2017

Correspondence Address:
Dr. Nachiappa Ganesh Rajesh
Department of Pathology, JIPMER, Puducherry - 605 006
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.198029

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How to cite this article:
Behera B, Chandrashekar L, Thappa DM, Rajesh NG. Solitary subcutaneous nodule over the right elbow. Indian J Dermatol 2017;62:108-10

How to cite this URL:
Behera B, Chandrashekar L, Thappa DM, Rajesh NG. Solitary subcutaneous nodule over the right elbow. Indian J Dermatol [serial online] 2017 [cited 2020 Sep 22];62:108-10. Available from: http://www.e-ijd.org/text.asp?2017/62/1/108/198029


A 25-year-old male presented with a solitary asymptomatic swelling over the right elbow of six months duration. There was no history of joint pain, breathlessness, diabetes, or any other systemic complaint. He was not on any medication. Cutaneous examination revealed solitary, non-tender, subcutaneous nodule measuring 4 mm × 4 mm over the right elbow [Figure 1]. The overlying skin was apparently normal. Other mucocutaneous, general, and systemic examinations were within normal limits. The histopathology of excised nodule revealed well-encapsulated subcutaneous tumor comprising of proliferating small-caliber blood vessels and adipose tissue [Figure 2]. The proliferating capillaries formed the bulk of the lesion and imparted an angiomatous pattern of growth with few of them containing thrombi in their lumen [Figure 3]. A variable amount of spindle cells, with few mast cells were present between the proliferating capillaries without any significant cellular atypia, pleomorphism, or mitotic figure [Figure 4].
Figure 1: Solitary skin-colored subcutaneous nodule over the right elbow

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Figure 2: Histology revealing well-encapsulated subcutaneous tumor comprising of proliferating capillary-sized blood vessels and adipose tissue (H and E, ×50)

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Figure 3: Proliferating capillaries impart an “angiomatous growth pattern” with a variable number of spindle cells. A few capillaries have thrombi (arrows) inside their lumen (H and E, ×100)

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Figure 4: The proliferating capillaries do not show any significant atypia, pleomorphism, or mitotic figures and have variable number of mast cells (arrow) interspersed within them (H and E, ×400)

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   References Top

1.
Calonje E, Brenn T, Lazar A, McKee PH, editors. McKee's Pathology of the Skin with Clinical Correlations. 4th ed. Philadelphia: Elsevier; 2012.  Back to cited text no. 1
    
2.
Lin JJ, Lin F. Two entities in angiolipoma. A study of 459 cases of lipoma with review of literature on infiltrating angiolipoma. Cancer 1974;34:720-7.  Back to cited text no. 2
    
3.
Sciot R, Akerman M, Dal Cin P, De Wever I, Fletcher CD, Mandahl N, et al. Cytogenetic analysis of subcutaneous angiolipoma: Further evidence supporting its difference from ordinary pure lipomas: A report of the CHAMP Study Group. Am J Surg Pathol 1997;21:441-4.  Back to cited text no. 3
    
4.
Kanik AB, Oh CH, Bhawan J. Cellular angiolipoma. Am J Dermatopathol 1995;17:312-5.  Back to cited text no. 4
    
5.
Sheng W, Lu L, Wang J. Cellular angiolipoma: A clinicopathological and immunohistochemical study of 12 cases. Am J Dermatopathol 2013;35:220-5.  Back to cited text no. 5
    


    Figures

  [Figure 1], [Figure 2], [Figure 3], [Figure 4]



 

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