Indian Journal of Dermatology
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E-IJD CASE REPORT
Year : 2016  |  Volume : 61  |  Issue : 1  |  Page : 120

Iatrogenic Cushing's syndrome after topical steroid therapy for psoriasis


1 Department of Internal Medicine, Division of Endocrinology, Trakya University, Edirne, Turkey
2 Department of Dermatology, Trakya University, Edirne, Turkey

Correspondence Address:
Birsen Sahip
Department of Internal Medicine, Medical Faculty, Trakya University, Edirne - 22030
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.174094

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Glucocorticoids are used for the treatment of many diseases, such as inflammatory, allergic, autoimmune, and neoplastic diseases. They can be used in the form of topical, oral, inhalable, rectal, and intra-articular agents. Many topical steroid-related iatrogenic Cushing's syndrome cases affecting especially children have been reported in the literature. Topical steroid-related Cushing's syndrome is rarely seen in adults. In this report, we present the case of a 32-year-old male patient with iatrogenic Cushing's syndrome related to long-term clobetasol propionate treatment for psoriasis. In the context of such treatment, the glucocorticoid withdrawal problem has to be overcome. At present there is no consensus on steroid withdrawal. Patients on long-term glucocorticoid treatment must be evaluated for potential adverse effects and withdrawal symptoms by their physician and their endocrinologist.


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