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E-IJD CORRESPONDENCE
Year : 2015  |  Volume : 60  |  Issue : 4  |  Page : 425
Human papillomavirus deoxyribonucleic acid in non-genital benign papillomatous skin lesion


1 Medical Center Unit, Shantou Medical Center, Shantou, China
2 Tropical Medicine, Hainan Medical University, Haikou, China

Date of Web Publication10-Jul-2015

Correspondence Address:
Sim Sai Tin
Medical Center Unit, Shantou Medical Center, Shantou
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0019-5154.160553

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How to cite this article:
Tin SS, Wiwanitkit V. Human papillomavirus deoxyribonucleic acid in non-genital benign papillomatous skin lesion. Indian J Dermatol 2015;60:425

How to cite this URL:
Tin SS, Wiwanitkit V. Human papillomavirus deoxyribonucleic acid in non-genital benign papillomatous skin lesion. Indian J Dermatol [serial online] 2015 [cited 2019 Sep 22];60:425. Available from: http://www.e-ijd.org/text.asp?2015/60/4/425/160553


Sir,

We would like to discuss on the report on "Human papillomavirus deoxyribonucleic acid in non-genital benign papillomatous skin lesion. [1]" Kambiz et al. reported that "Human papillomavirus deoxyribonucleic acid may not be detected in non-genital benign papillomatous skin lesions by polymerase chain reaction." [1] The result in this work is concordant with the previous report by Meibodi et al. [2] There are many possible explanations for this finding. The null prevalence might be due to no viral infection in the studies skin lesions or there might be some problem in the laboratory analytical process. If the nested polymerase chain reaction using specific selective primers is used, the detection rate can be significantly improve. [3] Finally, it should be noted that the chance for positive human papillomavirus deoxyribonucleic acid in genital benign papillomatous skin lesion is also not high. Reutter et al. reported that only 14.29% of genital benign papillomatous skin lesion was positive. [4]

 
   References Top

1.
Kambiz KH, Kaveh D, Maede D, Hossein A, Nessa A, Ziba R, et al. Human papillomavirus deoxyribonucleic acid may not be detected in non-genital benign papillomatous skin lesions by polymerase chain reaction. Indian J Dermatol 2014;59:334-8.  Back to cited text no. 1
[PUBMED]  Medknow Journal  
2.
Meibodi NT, Nahidi Y, Meshkat Z, Esmaili H, Gharib M, Gholoobi A. No Evidence of Human Papillomaviruses in Non-genital Seborrheic Keratosis. Indian J Dermatol 2013;58:326.  Back to cited text no. 2
[PUBMED]  Medknow Journal  
3.
Li YH, Chen G, Dong XP, Chen HD. Detection of epidermodysplasia verruciformis-associated human papillomavirus DNA in nongenital seborrhoeic keratosis. Br J Dermatol 2004;151:1060-5.  Back to cited text no. 3
    
4.
Reutter JC, Geisinger KR, Laudadio J. Vulvar seborrheic keratosis: Is there a relationship to human papillomavirus? J Low Genit Tract Dis 2014;18:190-4.  Back to cited text no. 4
    




 

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